2.5 Lipid Disorders

Card Set Information

Author:
xangxelax
ID:
256530
Filename:
2.5 Lipid Disorders
Updated:
2014-01-14 18:13:05
Tags:
CP2
Folders:
CP2
Description:
CP2
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user xangxelax on FreezingBlue Flashcards. What would you like to do?


  1. What are the 5 major risk factors for Coronary Heart Disease?
    • Cigarette smoking
    • Hypertension (blood pressure >= 140/90 mmHg or on meds)
    • Older age (Men>= 45; women >=55)
    • Low HDL cholesterol (<40 mg/dL)
    • Elder (family) hx of premature coronary artery disease (male first degree relative <55 y; female first degree relative <65)
  2. What are the ranges for a normal, borderline high, and high Total Cholesterol level?
    • Normal <200 mg/dL
    • Borderline High 200-239 mg/dL
    • High 240 mg/dL
  3. What are the ranges for a normal, borderline high, high and very high Triglycerides?
    • Normal <150 mg/dL
    • Borderline high 150-199 mg/dL
    • High 200-499 mg/dL
    • Very high >500 mg/dL
  4. What are the ranges for a low, normal, and high HDL Cholesterol?
    • Low <40 mg/dL Men, <50 mg/dL Women
    • Normal 40-50 mg/dL Men, 50-59 mg/dL Women
    • High 60 mg/dL Men and Women (negative risk factor)
  5. What is a negative risk factor for Coronary Heart disease?
    HDL >= 60 mg/dL
  6. What are the risk factors for hyperlipidemia - LDL?
    • Dietary factors (targeting)
    • Genetic factors

    • Secondary to:
    • Diseases- Nephrotic syndrome (renal disease)
    • Medications- Antipsychotic medications
  7. What are the risk factors for hyperlipidemia - Triglycerides?
    • Obesity
    • Physical inactivity

    • Other
    • Genetic factors
    • Dietary (high carb intake)
    • Diseases - Type 2 Diabetes
    • Medications - Protease inhibitors
  8. What are the risk factors for hyperlipidemia - HDL?
    • Obesity
    • Physical inactivity

    • Other
    • Genetic disorders
    • Dietary (high carb intake)
    • Diseases - Type 2 diabetes
    • Medications - Anabolic steroids
  9. What is the target LDL for low risk (0-1 risk factors)?
    <160 mg/dL
  10. What is the target LDL for moderate risk (>=2 risk factors)?
    <130 mg/dL
  11. What is the target LDL for high risk (CAD, CAD equivalent, 10y risk >20%)?
    <100 mg/dL
  12. What are some therapeutic lifestyle changes to target LDL?
    • Restrict total fat intake to 25-35% of total calories
    • Restrict saturated fat to <7% of total calories
  13. What medication can you take to target LDL?
    Statins
  14. What are some therapeutic lifestyle changes to target triglycerides?
    Weight loss can decrease triglyceride levels by 22%
  15. What are some medications to take to target triglycerides?
    Fibrates (lower triglycerides 50%)
  16. When should you treat triglycerides?
    If levels are >500 mg/dL (concern for pancreatitis)
  17. What is the primary target for therapy when treating hyperlipidemia?
    LDL cholesterol (major atherogenic lipoprotein)
  18. What are some therapeutic lifestyle changes that will increase HDL?
    Exercise can increase HDL by 1-4 mg/dL, depending on intensity of activity
  19. What is the tx plan if you have clinical atherosclerotic CVD (MI, angina, coronary revascularization, stroke, TIA, peripheral arterial disease)?
    High intensity statin therapy
  20. What is high intensity statin therapy?
    Daily dose lowers LDL cholesterol level by >=50% on average
  21. What is recommended when giving high intensity statin therapy?
    • Atorvastatn 40-80 mg
    • Rosuvastatin 20-40 mg
  22. What is moderate intensity statin therapy?
    Daily dose lowers LDL cholesterol level by 30 - <50% on average
  23. What is recommended when giving moderate intensity statin therapy?
    • Lower dosage of Atorvastatin and Rosuvastatin¬†
    • Generic drugs
  24. What do you do when a pt comes in who has Diabetes and is between 40-75 yr and has an LDL level between 70-189 mg/dL?
    • Calculate 10 yr risk of atherosclerotic CVD
    • If risk <7.5% = moderate intensity statin
    • If risk >7.5% = high intensity statin
  25. What do you do when a pt comes in who has no diabetes and is between 40-75 yr and has an LDL level between 70-189 mg/dL?
    • Calculate 10 yr risk of atherosclerotic CVD
    • If risk >=7.5%, mod-to-high intensity statin therapy
    • Under 7.5% = no statins
  26. What do you do when a pt comes in who has LDL cholesterol level of >=190 mg/dL?
    High intensity statin therapy

What would you like to do?

Home > Flashcards > Print Preview