quiz on 01/20/14

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Author:
anlind04
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256587
Filename:
quiz on 01/20/14
Updated:
2014-01-26 19:39:11
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quiz 01 20 14
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Description:
methylprednisolone sodium succinate ipratropium bromide albuterol sulfate magnesium sulfate
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  1. albuterol sulfate

    mechanism of action
    indications and field use
    B agonist(primarily B2) relaxes bronchial smooth muscle, resulting in bronchodilation; also relaxes vascular and uterine smooth muscle decreases airway resistance

    treatment of bronchospasm
  2. albuterol sulfate

    contraindications
    • synergistic with other sympathomimetics
    • caution with diabetes,hyperthyroidism and cerebrovascular disease
  3. albuterol sulfate

    adverse reactions
    • CV-dysrhythmias,tachycardia, periperal vasodilation
    • Resp-bronchospasm(rare paradoxical with excessive use)
    • CNS-nervousnesss,tremors
    • GI-vomit,nausea
    • Endocrine-hyperglycemia
  4. albuterol sulfate

    incompatibilites/drug interactions
    tricyclic antidepressants(TCA's) and monoamine oxidase(MAO) inhibitors 

    other sympathomimetics
  5. Albuterol sulfate

    adult dosage

    routes of adminstratoin
    give 2.5 mg premixed solution for inhalation via SVN with a mouth piece or in-line with a ventilatory device 

    • nebulized,mouth piece or in-line via mask
    • inhaler
    • ET/NT in-line
  6. Albuterol sulfate

    Onset of action
    peak effects
    duration of Action
    OOA 5-15 minutes 

    PE  30-2 hours 

    DOA  3-4 hours
  7. Ipratropium Bromide
    BN-
    CLass-
    atrovent

    anticholinergic,broncholdilator
  8. Ipratropium Bromide

    mechanism of action
    anticholinergic agent inhibit vagally-mediated reflexes by antagonizing action of acetylcholine
  9. ipratropium bromide

    indicatons and field use
    • bronchospasm with chronic obstructive pulmonary disease 
    • used alone or combination other broncholdilators especially beta adrenergics
  10. ipratropium bromide

    contraindications
    • hypersensitivity to ipratropium bromide or atropine and its derivatives 
    • caution-patients with narrow angle glaucoma
  11. Ipratropium bromide

    adverse reactions
    • RESP-coughing,sputum increased
    • CNS-Dizziness,insomnia,tremor,nervousness
    • GI-nausesa
  12. Ipratropium bromide

    incompatibilities/drug interactions
    none 

    can be used with albuterol for bronchodilators
  13. Ipratropium Bromide

    Adult dosage
    • 500mcg in 2.5 ml normal saline via SVN or inline ventilatory device
    • may mix one and one with albuterol
  14. Ipratropium bromide

    onset of action
    peak effects
    duration of action
    5-15 min

    60-120 min

    240-480 min
  15. magnesium sulfate

    BN
    class
    magnesium sulfate

    electrolyte, tocolytic
  16. Magnesium sulfate

    mechanism of action-

    • pharmacology-second most plentiful intracellular cation;essential to enhance intracellular potassium replenishment and activity of many enzymes; important role in neurochemical transmission and muscular excitabilitydecreases myocardial irritabilbity and neuromuscular irritability 
    • Clinical-cardia reduces ventricular irritablity,especially with associated with hypomagnesemia;inhibition of muscular excitability
  17. Magnesium sulfate

    indications and field use
    • torsade de pointes
    • VF/pulseless VT refactory to lidocaine and/or amiodarone
    • hypomagnesemia
    • pre-term labor
    • pregnancy-induced hypertension
    • hyperreactive airway-severe asthma
  18. magnesium sulfate

    contraindications
    • hypermagnesemia
    • caution-patients with impaired renal function and preexisting heart blocks
    • caution-when used with barbituates, narcotics or other hyponotics(MS due to the additive central depressive effects of magnesium)
  19. magnesium sulfate

    adverse reactions
    • CVS-hypotension,flushing,circulatory collapse,depressed cardiac funciton,heart block,asystole,smooth muscle relaxant
    • RESP-respiratory depression or paralysis
    • mother or child 24 hours later 
    • CNS-sweating,drowsiness,hypothermia,depressed reflexes progressing to flaccidity and paralysis 
    • mother and/or child 24 hours later
    • GI-nausea 
    • GU-mild diuretic
    • Meta-hypocalcemia,hypermagnesemia
  20. magnesium sulfate

    incompatibilites/drug interactions
    concurrent digitalization increases danger of dysrhythmias
  21. magnesium sulfate

    adult dosage
    • VF/pulseless VT-1-2 gm IV diluted in 50-100 ml NS or D5W or 1-2 minutes
    • torsade de pointes-1-2 Gm IV diluted in 50-100 ml NS or D5W administered over  1-2 minutes followed by smae amount infused over 1 hour
    • Hypomagnesemia-1-2 gm diluted in 50-100 ml NS or D5W admin iv push over 5-60 min
    • Respiratory/severe asthma-
    • initial infusion 2 gm magnesium sulfate mixed in 50 ml NS or D5W infused IV using microdrip tubing over 5-10 minutes-stop if hypotension,respiratory depression or bradycardia develop
  22. methylprednisolone sodium succinate
    Solu-medrol
  23. Solu-medrol
    class
    Corticosteroid ,glucocorticoid,steroid ,antiinflammatory
  24. Solu-medrol 
    MOA
    Causes complex reactions thata are responsible for anti inflammatory and immunosuppressive effects 

    thought to stabilize cellular and intracellular membranes
  25. Solu medrol 

    indications and field use
    Reactive airway disease :acute exacerbation of emphysema,chronic bronchitis asthma anaphylaxis burns potentially involving the airway

    acute spinal cord trauma 
  26. Solu medrol

    contraindications
    adverse reactions
    drug interactions
     
    • Preterm infants
    • none 
    • none
  27. Solu medrol
    Drug dosage

    125 mg slow IV push 
  28. Solu medrol 

    onset of actions 
    peak effects 
    duration of action 
    • 1-6 hours 
    • 8 hours
    • 18-36 hours 

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