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Pathology
- the investigation of structural alterations in cells, tissues, and organs, which
- can help identify the cause of a particular disease.
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pathogenesis
the pattern of tissue changes associated with the development of disease.
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Etiology
refers to the study of the cause of disease.
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idiopathic
Diseases that have no identifiable cause
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iatrogenic
Diseases that occur as a result of medical treatment
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Nosocomial
Diseases that are acquired as a consequence of being in a hospital environment
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Diagnosis
naming or identification of a disease.
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Prognosis
expected outcome of a disease.
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Acute disease
the sudden appearance of signs and symptoms that last only a short time.
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Chronic disease
- develops more slowly and the signs and symptoms last for a long time, perhaps for a
- lifetime. Chronic diseases may have a pattern of remission and exacerbation.
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Remissions
periods when symptoms disappear or diminish significantly
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Exacerbations
periods when the symptoms become worse or more severe.
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Complication
- the onset of a disease in a person who is already coping with another existing disease.
- For example, a person who has undergone surgery to remove a diseased appendix
- may develop the complication of a wound infection or pneumonia.
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Sequelae
- unwanted outcomes of having a disease or are the result of trauma, such as paralysis
- resulting from a stroke or severe scarring resulting from a burn.
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Clinical manifestations
the signs and symptoms or evidence of disease.
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Signs
- objective alterations that can be observed or measured by another person, measures of
- bodily functions such as pulse rate, blood pressure, body temperature, or white
- blood cell count.
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Different types of signs
- Some signs are local such as redness or swelling, and other signs are systemic
- such as fever.
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Symptoms
- subjective experiences reported by the person with disease, such as pain, nausea, or
- shortness of breath, and they vary from person to person.
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Prodromal period
- The prodromal period of a disease is the time during which a person experiences vague
- symptoms such as fatigue or loss of appetite before the onset of specific signs
- and symptoms.
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Insidious symptoms
- refers to vague or nonspecific feelings and an awareness that there is a change within
- the body.
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Latent Period
- a time during which no symptoms are readily apparent in the affected person, but
- the disease is nevertheless present in the body; an example is the incubation
- phase of an infection or the early growth phase of a tumor.
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Syndrome
- a group of symptoms that occur together and may be caused by several interrelated
- problems or a specific disease. Severe acute respiratory syndrome (SARS), for
- example, presents with a set of symptoms that include headache, fever, body
- aches, an overall feeling of discomfort, and sometimes dry cough and difficulty
- breathing.
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Disorder
- an abnormality of function; this term also can refer to an illness or a particular
- problem such as a bleeding disorder.
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Epidemiology
- the study of tracking patterns or disease occurrence and transmission among
- populations and by geographic areas.
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Incidence
Incidence of a disease is the number of new cases occurring in a specific time period.
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Prevalence
Prevalence of a disease is the number of existing cases within a population during a specific time period.
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Risk factor/predisposing factors
- risk factors increase the probability that disease will occur, but these factors are not the cause of disease. Risk factors include heredity, age, gender, race,
- environment, and lifestyle.
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precipitating factor
a condition or event that does cause a pathologic event or disorder. For example, asthma is precipitated by exposure to an allergen, or angina (pain) is precipitated by exertion.
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