DMARDs.txt

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Author:
BELISA78
ID:
25799
Filename:
DMARDs.txt
Updated:
2010-07-06 01:05:43
Tags:
PT pharmacology
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Description:
review of disease modifying anti-rheumatic drugs
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  1. DMARD's: Disease modifying anti-rheumatic drugs are used with active, continuing inflammatory disease.
    Methotrexate

    Anti-cytokines
  2. an enzyme inhibiting drug. used as an anti-cancer agent as well as DMARD
    Methotrexate
  3. This DMARD binds with TNF (anti-human tumor necrosis factor-alpha) and inactivates it.
    Anti-cytokines
  4. This DMARD inhibits T & B cell activity involved in the autoimmune process:
    Leflunomide (Arava)
  5. This DMARD is used in combo with methotrexate:
    infliximab
  6. This DMARD blocks interleukin receptors which diminshes bone erosion and cartilage destruction:
    Anakinra (Kineret)
  7. these are side affects of what DMARD's:

    mental status changes
    retinopathy
    muscle weakness with decreased DTR's
    Anti-malarials
  8. these are side affects of what DMARD's:

    GI problems
    skin problems
    blood disorders
    bone marrow depression
    sulfa drugs, penicillamine, and imuran (immunosuppressant)
  9. a potent immunosuppressant that reduces T & B cell activation:
    cyclosporine (Neoral)

    ***Look for any change in RA or general health status due to many possible drug interactions***

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