Microbiology

Card Set Information

Author:
Em262
ID:
258009
Filename:
Microbiology
Updated:
2014-01-23 05:53:06
Tags:
Organisms
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Description:
Antibiotics
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  1. Penicillin effective against
    Gram-positive bacteria
  2. Penicillin mechanism of action
    Inhibits peptidoglycan synthesis and murein assembly- steps in cell-wall synthesis
  3. Ampicillin, Amoxicillin effective against:
    • Gram-positive bacteria
    • Gram-negative bacteria
  4. Amoxicillin, Ampicillin mechanism of action
    Inhibits peptidoglycan synthesis and murein assembly- steps in cell-wall synthesis
  5. Augmentin (clavulonic acid + amoxicillin)
    Gram-postive and gram-negative bacteria
  6. Augmentin (clavulonic acid + amoxicillin) mechanism of action
    Inhibitor of bacterial beta-lactamases
  7. Streptomycin and gentamicin (aminoglycosides)
    Gram-positive and gram-negative bacteria
  8. Streptomycin mechanism of action
    Inhibits translation (protein synthesis)
  9. Vancomycin (glyocopeptide)
    Gram-positive bacteria especially Staph. aureus.
  10. Vancomycin mechanism of action
    Inhibits steps in murein (peptidoglycan) biosynthesis and assembly
  11. Macrolides- erythromycin
    Gram-positive bacteria, Gram-negative bacteria not enterics, Neisseria, Legionella, Mycoplasma
  12. Macrolides- erythromycin mechanism of action
    Inhibit translation (protein synthesis)
  13. Rifampicin
    Gram-positive and Gram-negative bacteria, Mycobacterium tuberculosis
  14. Rifampicin mechanism of action
    Inhibits transcription (bacterial RNA polymerase)
  15. Fluoroquniolones- ciprofloxacin
    Gram-negative and some  Gram-positive bacteria (Bacillus anthracis)
  16. Ciprofloxacin mechanism of action
    Inhibits DNA replication
  17. Side-effect of Chloramphenicol
    Aplastic anaemia

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