Osteoporosis agents or interventions
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what vitamins are important in the prevention of osteoporosis?
what does vitamin D do to bone?
facilitates absorption of calcium from GI tract
what does calcium do to bone?
increases bone density
what are other non-dietary ways to prevent osteoporosis?
weight bearing exercises
decrease alcohol consumption
decrease caffeine intake (increases calcium excretion)
these anti-osteoporitic drugs increase bone mass density and decrease osteoclastic bone resorption.
Alendronate (fosamax) and risedronate (actonel)
Hormone replacement therapy
this drug is useful in paget's disease and heterotrophic ossification
this drug contains parathyroid hormone and raloxifene ( evista), a selective antiestrogen agent.
it is used for prevention in post menopausal women.
this drug is a hormone ethat diminishes osteoclastic activity, is often admin as a nasal spray, and can be used for paget's disease but cannot prevent osteoporosis.
this therapy used estrogen plus progestin but has been discontinued due to increased risk of breast cancer and CV problems
hormone replacement therapy.
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