Therapeutics - IP anticoagulation 2

Card Set Information

Author:
kyleannkelsey
ID:
260966
Filename:
Therapeutics - IP anticoagulation 2
Updated:
2014-02-09 11:20:01
Tags:
Therapeutics IP anticoagulation
Folders:
Therapeutics - IP anticoagulation 2
Description:
Therapeutics - IP anticoagulation 2
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user kyleannkelsey on FreezingBlue Flashcards. What would you like to do?


  1. What is the dose of Enoxaparin for Treatment of VTE in a patient with a CrCl of >30?
    1 mg/kg SQ Q12H (inpatient only: 1.5 mg/kg SQ Q24H)
  2. What is the dose of Enoxaparin for Treatment of VTE in a patient with a CrCl of <30?
    1 mg/kg SQ Q24H (50% less than normal) – Should just use unfractionated Heparin instead
  3. What are the therapeutic dose ranges for Dalteparin (fragmin) in the treatment of VTE?
    7500 – 18,000 U
  4. What dose of Dalteparin (fragmin) would you give for prevention of VTE to a patient undergoing Abdominal surgery and not a at a high risk for VTE?
    • 2,500 IU SQ QD
    • start 1-2h BEFORE surgery
  5. What dose of Dalteparin (fragmin) would you give for prevention of VTE to a patient undergoing Abdominal surgery with high risk for VTE?
    • 5,000 IU SQ QD
    • Start: evening BEFORE surgery
  6. What is the normal dose of Dalteparin (fragmin) given to general medical patients for prevention of VTE?
    5000U SQ QD
  7. What dose of Dalteparin (fragmin) would you give for prevention of VTE to a patient undergoing Hip replacement surgery?
    5000 IU SQ QD > 12 hours AFTER period
  8. What is the Treatment dose for Tinazapam (Innohep) for VTE for patient with CrCl>30?
    175 U/kg SQ QD
  9. What dose adjustments would be made for Tinazapam (Innohep) for VTE for patient with CrCl<30?
    Based on Check anti-factor Xa levels
  10. Bariatric dosing for VTE prophylaxis with Enoxaprin, what dose would you give a person w/ a BMI of 40-49?
    40 mg SQ Q12H
  11. Bariatric dosing for VTE prophylaxis with Enoxaprin, what dose would you give a person w/ a BMI of 50-59?
    60 mg SQ Q12H
  12. Bariatric dosing for VTE prophylaxis with Enoxaprin, what dose would you give a person w/ a BMI of >60?
    80 mg SQ Q12H
  13. What dose of Fondaparinux (Atrixia) would you give for prevention of VTE?
    2.5 mg SQ QD, CI in <50 kg
  14. What dose of Fondaparinux (Atrixia) would you give for treatment of VTE?
    • 5mg (body weight < 50 kg)
    • 7.5 mg (body weight 50-100 kg)
    • 10 mg (body weight > 100 kg)
  15. Under what conditions is Fondaparinux contraindicated?
    CrCl<30
  16. What dose of Argatroban would you give if a patient has normal hepatic function?
    2 mcg/kg/min
  17. What dose of Argatroban would you give if a patient has Child-Pugh score of >6 or Serum Bilirubin of > 1.5 mg/dL?
    0.5 mcg/kg/min
  18. What dose of Argatroban would you give if a patient has HF, multi organ system failure or severe anasarca?
    0.5-1.2 mcg/kg/min
  19. What is the FDA labeled Indication for Argatroban?
    Coronary artery thrombosis in patients with or at risk of HIT
  20. How do you monitor Argatroban?
    Dose adjusted to maintain aPTT ratio of 1.5-3x baseline values
  21. After HIT you should postpone Warfarin until what indicator?
    Platelet count is >150,000
  22. What is the dose of UFH for prophylaxis?
    5000U q8-12h SQ
  23. What dose of Unfractionated heparin would you give if a patient had Venous Thromboembolism?
    • Bolus: 80 U/kg (max: 10,000 U)
    • Infusion: 18 U/kg/hr (max: 2,300 U/hr)
  24. What dose of Unfractionated heparin would you give if a patient had Acute coronary syndrome?
    • Bolus: 60-70 U/kg (max: 5,000 U)
    • Infusion: 12-15 U/kg/hr)
  25. What dose of Unfractionated heparin would you give if a patient was also receiving fibrinolytic agents?
    • Bolus: 60 U/kg (max: 4,000 U)
    • Infusion: 12 U/kg/hr (max: 1,000 U/hr)
  26. What is a normal VTE prophylactic dose of Enoxaparin for a general patient with a CrCl>30?
    40 mg SQ QD
  27. What is a normal VTE prophylactic dose of Enoxaparin for a general patient with a CrCl<30?
    30 mg SQ QD
  28. What is a normal VTE prophylactic dose of Enoxaparin for a Hip replacement patient with a CrCl>30?
    • 12 hours after surgery: 30 mg SQ Q12H
    • 12 hours BEFORE or AFTER surgery: 40 mg SQ QD
  29. What is a normal VTE prophylactic dose of Enoxaparin for a Hip replacement patient with a CrCl<30?
    30 mg SQ QD
  30. What is a normal VTE prophylactic dose of Enoxaparin for a Knee-replacement patient with a CrCl>30?
    30 mg SQ Q12H >12 hours BEFORE surgery
  31. What is a normal VTE prophylactic dose of Enoxaparin for a Knee-replacement patient with a CrCl<30?
    30 mg SQ QD >12 hours AFTER surgery
  32. What is a normal VTE prophylactic dose of Enoxaparin for an Abdominal surgery patient with a CrCl>30?
    40 mg SQ QD >2 hours BEFORE surgery
  33. What is a normal VTE prophylactic dose of Enoxaparin for an Abdominal surgery patient with a CrCl<30?
    30 mg SQ QD 12-24 hours AFTER surgery
  34. Which anticoagulants are contraindicated with a CrCl of <30?
    Fondaparinux and Rivaroxaban
  35. Which anticoagulants require a dose adjustment with a CrCl of <30?
    Enoxaparin, Dagbigatran, Tinazapan, Daltaparin, Bivalirudin

What would you like to do?

Home > Flashcards > Print Preview