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Of the anticoagulants discussed, Which are SQ?
- UFH (prophylactic dosing)
Of the anticoagulants discussed, Which are IV?
UFH (treatment dosing)
Of the anticoagulants discussed, which are Oral?
Rivaroxaban and Warfarin
Which anticoagulant should you bridge with Warfarin in the evening?
Which anticoagulants have a black box warning for spinal or epidural puncture leading to Hematoma?
- Fonduparinux and Rivaroxaban (UFH maybe?)
Which anticoagulant should only be given for treatment of VTE in Cancer patients?
Which anticoagulant should not be bridged with Warfarin?
Dalteparin and Rivaroxaban
What is the trade name for Dalteparin?
What is the brand name for Fragmin?
What is the trade name for Fondaparinux?
What is the brand name for Arixtra?
What is the trade name for Rivaroxaban?
What is the brand name for Xarelto?
What should you monitor for prophylactic anticoagulant use?
- S/S of bleeds
- Adverse events
- Pain/irritation/bruising at injection site
- Complete CBC Periodically
Can you bridge Enoxaparin with Warfarin?
Rivaroxaban is metabolized by what enzymes?
- CYP3A5 and P-gp
What drugs are contraindicated with Rivaroxaban?
- Protease inhibitors
Antiplatelets/NSAIDs and St. Johns Wort
Can you use Warfarin during pregnancy?
What is the pregnancy category for Rivaroxaban?
What is the risk factors for Provoked VTE?
- oral contraceptives
Rivaroxaban was found to be more efficacious than Enoxaparin in what situation?
Following total knee or Hip replacement
Why should you cautiously use Rivaroxaban in patients over 75?
Diminished renal function
What is the trade name for Innohep?
What is the brand name for Tinazaparin?
Is Rivaroxaban safe for lactating mothers?
Which anticoagulants should be given in Combo with Warfarin in the treatment of VTE?
Enoxaparin, Tinazeparin, Fonduparinux, UFH