Therapeutics: 3

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Author:
kyleannkelsey
ID:
261225
Filename:
Therapeutics: 3
Updated:
2014-05-06 16:00:15
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Therapeutics: 3
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  1. AIOH Antacids (Alternagel, Amphogel)
    • For many years, the agent of choice
    • Possible side effects: Osteomalacia, encephalopathy
    • Now recognized problem of aluminum intoxication with long term use
  2. Magensium hydroxide (Milk of Magnesia)
    1-6 tabs/dayCan cause diarrhea
  3. Calcium carbonate (Tums): 1-2 g/each meal
    • Inexpensive, tablets can be crushed
    • Numerous dosage formulations
    • Not for pts with hypercalcemia
  4. Calcium acetate (Phos-Lo)
    • 2 tabs/caps each meal initially (1 tab/cap = 667 mg)
    • Maintenance dose is 3-4 caps/tans with each meal
    • Less systematic absorption than calcium carbonate
  5. Sevelamer carbonate (Renvela)
    • Replaced sevelamer hydrochloride (Renagel)
    • Exacerbated metabolic acidosis in dialysis pts
    • Cationic polymer, contains neither calcium or aluminum
    • 800-1600 mg tid with meals
    • Available in tabs & powder suspension
  6. Lanthanum carbonate (Fosrenol)
    • Initial dose 250-500 mg PO 3x daily to max of 3750 mg/d
    • Most require 1500-3000 mg/day

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