Pharmacology Antidepressants 2

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Author:
kyleannkelsey
ID:
262244
Filename:
Pharmacology Antidepressants 2
Updated:
2014-02-16 13:49:30
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Pharmacology Antidepressants
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Pharmacology Antidepressants 2
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Pharmacology Antidepressants 2
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  1. What is the MOA of TCAs?
    Inhibit the reuptake of NE and Serotonin in the CNS
  2. TCAs are used to treat what disorder?
    Panic disorder, Enuresis, Neuropathic pain and Depression
  3. What receptors can TCA’s interact with?
    SERT (serotonin), NET (NE), Histamine, Muscarinic (1 and 2), alpha-1-adrenergic, some: voltage gated ion channels
  4. What drug is the most selective inhibitor of serotonin reuptake studied to date?
    Escitalopram
  5. What is Fluoxetine/Prozac indicated for?
    Depression, PMDD, Bulimia and Geriatric depression
  6. Does Fluoxetine/Prozac have a long or short half life?
    Long
  7. What is Sertraline (Zoloft) indicated for?
    PTSD, PMDD, OCD in children, Major depressive disorder
  8. Which SSRI has one label indication and what is the indication?
    Citalopram, Depression ( though used for OCD and other SSRI indications)
  9. Cymbalta (Duloxetine)
    SNRI
  10. Svella (milnacipran)
    SNRI
  11. Effexor (venlafaxine)
    SNRI
  12. Pristiq (desvenlafaxine)
    SNRI
  13. Edronax (reboxetine)
    NaRI

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