they interfere w/ the clotting the clotting mechanism of the blood.
warfarin and anisindione interfere with the manufacturing of vitamin k-dendent clotting factors by the liver. This results in the depletion of clotting factors II(prothrombin) which is ESSENTIAL 4 clotting
Nurse = Heparin cant be taken orally cuz its inactivated by gastric acid in the stomach so it has 2 be injected.
What are anticoagulants used for?
Prophylaxis and tx of DVT
Tx of atrial fibrillation w/ embolization
Tx of PE
Adjuvant tx of MI
Prevention of thrombus formation after valve replacement surgery
Parenteral anticoagulants used 4:
prevention of postop DVT and PE in certain pts hving surgery like ABD surgery.
prevention of clotting in arterial and heart surgery, equipment used 4 extracorporeal, dialysis procedures, blood transfusions, blood samples 4 lab.
prevention of repeat cerebral thrombosis pts who had a stroke
tx of coronary occlusion, acute MI, peripheral arterial embolism
dx & tx of DIC, severe hemorrhagic disorder
maintaining patency of IV caths
What are adverse reactions of anticoagulants?
Bleeding may be seen in many areas of the body ex bruising and petechia, bladder, bowel, stomach, uterus, and mucous membranes.