MO: What is interaction of pancreas, liver & adrenals?
Endocrine portion of pancreas is a small cluster of cells called Islets of Langerhans (about 1% of pancreas). Islets of Langerhans contain Alpha cells that make Glucagon and Beta Cells that make Insulin. Insulin & glucagon signal the liver to either store or release glycogen.
Liver is primary organ responding to hormone messages (insulin/glucagon/cortisol/ephinephrine) regarding high or low blood sugar. A healthy liver is essential to good blood sugar regulation. Stores glucose as glycogen; breaks down glycogen to form glucose; makes glucose from proteins (gluconeogenesis); makes ketones. If the liver and muscle fiber glycogen stores are full, the liver converts the remaining glucose to triglycerides and cholesterol for storage.
Adrenals are body's emergency response system. Produce hormones that raise blood sugar in the event glucagon is not doing its job or in other emergency situations when additional glucose is required. Hormones are cortisol & epinephrine.