Pharmacodynamics

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Author:
Anonymous
ID:
264531
Filename:
Pharmacodynamics
Updated:
2014-03-01 16:02:56
Tags:
Pharmacodynamics
Folders:
Pharmacology,Test 1
Description:
Pharmacology Test 1
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  1. Pharmacodynamics
    The study of the biochemical and physiologic effects of drugs and their mechanism of action
  2. Drug-receptor binding is stimulated by...
    chemical bonding
  3. Irreversible binding
    when the ligand does not dissociate for a long period of time
  4. Ligand
    An endogenous or exogenous molecule that bind with a molecular target (receptor)
  5. What determines quantitative relationship between dose and drug concentration
    Affinity
  6. First messengers
    Ligands, receptors response to lignads which starts the cascade of changes in the cell
  7. Second messengers
    components of the cascade
  8. Full agonist
    A ligand that binds to activates a receptor with maximal effect even with only a few receptors activated
  9. Partial agonist
    A ligand that bind to and activates the receptor with submaxial effects even with all the receptors activated
  10. Which bond creates irreversible bonds?
    covalent- shared electrons with a strong attraction
  11. Which bonds create reversible bonds?
    Noncovalent- oppositely charged electrons, weaker attraction
  12. chemical antagonist
    drug forms ionic bond with second drug, making it unavailable for interaction
  13. Physiological antagonist
    opposite affects of insulin to control hyperglycemia caused by glucocoticoid

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