Card Set Information
Pharmacology Test 1
The study of the biochemical and physiologic effects of drugs and their mechanism of action
Drug-receptor binding is stimulated by...
when the ligand does not dissociate for a long period of time
An endogenous or exogenous molecule that bind with a molecular target (receptor)
What determines quantitative relationship between dose and drug concentration
Ligands, receptors response to lignads which starts the cascade of changes in the cell
components of the cascade
A ligand that binds to activates a receptor with maximal effect even with only a few receptors activated
A ligand that bind to and activates the receptor with submaxial effects even with all the receptors activated
Which bond creates irreversible bonds?
covalent- shared electrons with a strong attraction
Which bonds create reversible bonds?
Noncovalent- oppositely charged electrons, weaker attraction
drug forms ionic bond with second drug, making it unavailable for interaction
opposite affects of insulin to control hyperglycemia caused by glucocoticoid