neurobio 9 ch 6 of bear's book: neurotransmitter systems part 2 (ACh ligand chatecholaminergic do

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Author:
mikepl103
ID:
265434
Filename:
neurobio 9 ch 6 of bear's book: neurotransmitter systems part 2 (ACh ligand chatecholaminergic do
Updated:
2014-03-07 17:06:51
Tags:
neurobio bear book neurotransmitter systems part ACh ligand chatecholaminergic dopamine norepinephrine epinephrine transmitter gated channels
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2014,biology,neurobiology
Description:
neurobio 8 ch 6 of bear's book: neurotransmitter systems part 1 (ACh, ligand, chatecholaminergic, dopamine, norepinephrine, epinephrine, transmitter-gated channels)
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  1. each G protein has how many subunits and what are they called?
    three subunits, alpha, beta, and gamma.
  2. what is the configuration of the g protein in its resting state?
    the entire complex is floating, attached to the cell membrane, not far from the GPCR. The alpha subunit has GDP attached to it.
  3. what happens immediately once the G protein complex comes into contact with a transmitter-bound receptor?
    it releases GDP and exchanges it for a GTP. It then splits into the parts, the alpha subunit, and the gamma/beta complex.
  4. what can the alpha subunit and gamma/beta complex do once they are activated?
    they can influence various effector proteins,
  5. true or false, the alpha subunit of the G protein is an enzyme that eventually breaks down GTP ointo GDP, terminating its own activity?
    true
  6. G proteins can activate one of two different effector proteins. What are they?
    ion channels and other effector enzymes
  7. what is the most common excitatory neurotransmitter in the brain?
    glutamate
  8. what is divergence?
    the ability of one transmitter to activate more than one subtype of receptor
  9. what is convergence?
    when multiple neurotransmitters activate their own receptor type and converge to affect the same effector systems

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