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2014-03-12 08:22:54
Hematology Clincial Exam Review

Hematology Clinical Exam
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  1. Erythrocytes that vary in size from the normal 6-8 microns are described as exhibiting:
  2. Mean Cell volume (MCV) is calculated using the formula:
    Hct x 10 / RBC count
  3. Given the following data:
    Hgb 15
    RBC 4.5x10^6
    Hct 47%

    Caluclate the Mean Corpuscular Hemoglobin Content (MCHC)
  4. A manual WBC count gave a total of 36 cells counted in all 9 square millimeters of a Neubauer ruled hemocytometer. A 1:10 dilution was used; what is the WBC count?
    4.0 x 10^9
  5. What staining method is used most requently to stain and count reticulocytes?
    supravital staining
  6. A total leukocyte count is 10 x 10^9 and 15 NRBCs are seen per 100 WBCs on the differential. What is the corrected leukocyte count?
    8.7 x 10^9
  7. Using a hematology analyzer, an increased RDW should correlate with:
  8. Spherocytes differ from normal cells in all of the following except:
    increased deformability
  9. Which of the following is the anticoagulant of choice for patients exhibiting platelet clumping?
    Sodium citrate
  10. What reagents are used in the PT test?
     thromboplastin and calicum chloride
  11. The following factors are measured by either the PT or APTT except:
    factor XIII
  12. Blood is diluted 1:200, and a platelet count is performed. 174 platelets were counted in the center square millimeter on one side of the hemacytometer and 178 on the other side. What is the total platelet count?
    352 x 10^3
  13. All of the following physiological conditions may be associated with thrombocytopenia except:
    increased production of pluripotential stem cells
  14. Which of the following coagulation test results is normal in a patient with classic von Willebrand's disease?
    platlet count
  15. The hormone responsible for increasing the production of red blood cells is:
  16. When one is estimating the size of a red blood cell on a peripheral smear, which of the following white cells is approximately the same size?
  17. The last erythrocyte stage to contain a nucleus is called the:
    orthochromic normoblast
  18. Red blood cells with a MCV of 105 fL should correlate with a blood smear appearance of:
  19. In a patient with a hypochromic microcytic anemia, it is necessary to distinguish between iron deficiency and:
    heterozygous thalassemia
  20. Basophilic stippling of red cells represents:
    aggregated ribosomes
  21. "Shift to the left" when used in describing cell population, indicates:
    an increase in immature cells
  22. Production of primary granules ceases and production of secondary granules commences with what cell stage?
  23. A failure of granulocytes to divide beyond the band or two-lobed stage is observed in:
    Pelger-Huet anomaly
  24. In which disease is the Philadelphia chromosome a characteristic finding:
    chronic myelogenous leukemia
  25. The following erythrocyte indices are obtained for a specimen:
    MCV 88
    MCH 30
    MCHC 34

    On a wright-stained smear, these cells should appear:
    normochromic, normocytic
  26. A phase platelet count was performed and the total platelet count was 356 x 10^3. 10 fields on the stained blood smear were examined for platelets and the results per field were: 16 18 15 20 19 17 19 18 20 16
    The next step would be to?
    report the phase-platelet count since it correlated well with the slide
  27. A patient's hematologic results from an electrical impedance instrument are:
    WBC 1.0 x 10^9
    RBC  3.83 x 10^12
    HGB 11.5
    HCT  0.34
    PLT 60 x 10^9

    Blood smear evaluation for QC purposes reveals acceptable cell distribution; normochromic, normcytic RBCs; 2 leukocytes per 40x field; and 10 platelets per oil-immersion field. The next step would be:
    repeat the platelet count
  28. Which characteristic differeniates the myelocyte from ther myelocytic cells?
    presence of a coarse nuclear chromatin
  29. Thalassemias are characterized by:
    decreased rate of globin synthesis
  30. Auer rods are most likely present in which of the following?
    acute granulocytic leukemia
  31. Elevation of the total granulocyte count above 9.0 x 10^3 is termed:
    absolute neutrophilic leukocytosis
  32. Elevation of the total white cell count above 10 x 10^9 is termed:
  33. The majority of the iron in an adult is found as a constituent of
  34. Which of the following is associated with May-Hegglin anomaly?
    dohle boies and giant platelets
  35. Heinz bodies are:
    denatured HGB inclusions that are readily removed by the spleen
  36. Evidence indicates that the genetic defect in thalassemia usually results in:
    a quatitative deficiency in RNA resulting in decreased globin chain production
  37. A patient with a high cold agglutinin titer has an elevated MCV, MCH, and MCHC. Individual RBCs appear normal on the stained smear, but agglutinates are noted. The appropriate course of action would be to:
    repeat the determination using a prewarmed microsample of diluted blood
  38. An enzyme deficiency associatd with a moderate to severe hemolytic anemia after the patient is exposed to ertain drugs and characterized by red cell inclusions formed by denatured Hgb is:
    G-6-PD deficiency
  39. Which of the following is most closely associated with chronic myelogenous leukemia?
    Philadelphia chromosome
  40. Which of the following is most closely associated with chronic myelomonocytic leukemia?
  41. The mean for hemoglobin is 13.0 and the standard deviation is 0.15. The acceptable control range is +-2 standard deviations, What are the allowable limits for the control?
    12.7 - 13.3
  42. The following CBC results were obatined from an automated cell counter on a patient sample with lipemic plasma:
    WBC 7.2
    RBC 3.5
    HGB 13.8
    HCT 33.5
    MCV 92
    MCH 39.4
    MCHC 41

    Which of the following groups of tests would probably be in error?
    Hgb, MCH, MCHC
  43. Heparin acts by:
    inhibiting thrombin
  44. A patient has been taking aspirin regularly for arthritic pain. Which one of the following tests is most likely to be abnormal in this patient?
    platelet function test
  45. APTT purpose
    monitors heparin therapy
  46. a 1:200 dilution of a patient's sample was made and 336 red cells were counted in an area of 0.2. What is the RBC count?
  47. Blood collected in EDTA undergoes which of the following changes if kept at room temperature for 6-24 hours?
    increased Hct and MCV
  48. 153 NRBCs are reported on a 100 cell differential. The uncorrected WBC count is 11.9 What is the corrected count?
  49. The rule of three means that the
    HCT is three tiems the HGB
  50. The most characteristic morphological features of atypical lymphocytes include:
    coarse nuclear chromatin and basophilic cytoplasm