Life Support BCS

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Author:
Anonymous
ID:
266804
Filename:
Life Support BCS
Updated:
2014-03-17 18:59:59
Tags:
Life Support
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Description:
Life Support
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  1. ACE-Inhibitors
    • Captopril/Enalapril
    • Inhibit ACE (angiotensin converting enzyme)
    • Competitive inhibitor
    • Increase bradykinnin = peptide = vasodilator
    • Captopril = cough
    • Renal artery stensosis
    • Hyperkalemia
    • Angioedema
  2. Main Contraindications ACE Inhibitors
    • Artery stenosis
    • Kidney disease
    • Asthma
    • Pregnancy
    • Low sodium
    • High potassium
    • Angioedema (Fx - Enalapril)
  3. RAAS System Effects
    • Increase SNS
    • Tubular Na/Cl reabsorption (water retention)
    • Tubular K excretion
    • Adrenal gland cortex (more aldosterone so more of above tubular)
    • Anteriola vasoC
    • ADH secretion leading to water reabsorption
  4. Angiotensin-Receptor Blocker
    • Losartan
    • Inhibit angiotensin
    • AT1
    • Hypotension
    • Tachycardia
    • Bradycardia (vagal nerve)
  5. Contraindications of ARB
    Diabetes
  6. Calcium channel blocker
    • Nimodipine/Verapamil
    • Stop smooth muscle contraction
    • Blocks L-type calcium channels
  7. Contraindications CCB
    • Left ventricular hypertension
    • AV-block (2nd or 3rd degree)
    • Atrial flutter
    • Atrial fibrolation
  8. Thiazide Diuretic
    • Bendroflumethiazide/Flusomide
    • Decrease kidney reabsorption
    • Vasodilator
    • Act on tube of nephron
    • Blocks NKCC2
    • Fluid deplesion / Dehydration / hypokalemia / Weight loss / Tinnitus / Hearing loss
  9. Contraindications of Thiazide Diuretic
    • Asthma
    • Anuria
  10. ß-Blocker
    • Atenolol/
    • Blocks ß1 receptor
    • Therefore block SNS
    • Heart block / Cardiac failure / Bronchospasm / Hypoglycaemia
  11. Contraindicaions ß-blocker
    • Sinus bradicardia
    • Heart block
    • Cardiogenic shock
    • Cardiac failure
    • Hypersensitivity
  12. alpha blocker

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