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organs
organization of different tissues into functional units
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tissues
groups of cells with a similar appearance and a common function
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physiology
biological function
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organ system
groups of organs that work together to provide an additional level of organization and coordination
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epithelial tissue
sheets of closely packed cells which cover the outside of the body and line organs and cavities
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epithelium
lines the intestines and secretes digestive juices and absorbs nutrients
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basal lamina
a dense mat of extracellular matrix that separates the epithelium from the underlying tissue
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nervous tissue
functions in the receipt, processing, and transmission of information
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neurons
the basic units of the nervous system
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skeletal muscle
responsible for voluntary movements; the arrangement gives them a striped appearance
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striated muscle
skeletal muscle
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smooth muscle
lacks striations and has spindle-shaped cells, is found in the walls of many internal organs. responsible for involuntary activities, such as churning of the stomach and constriction of arteries
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cardiac muscle
striated like skeletal muscle, forms the contractile wall of the heart
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connective tissue
consists of cells scattered through an extracellular matrix, often consisting of a web of fibers embedded in a liquid, jellylike, or solid foundation. Includes loose connective tissue, fibrous connective tissue, and blood and bone
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regulator for an environmental variable
uses internal mechanisms to control internal change in the face of external fluctuation
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conformer for an environmental variable
allows its internal condition to change in accordance with external changes
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interstitial fluid
the fluid that surrounds body cells
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homeostasis
"steady state" as in the steady body temperature or the stable concentration of solutes in animals
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set point
a particular value for the variable being maintained by homeostasis, such as 37 C for human body temperature
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stimulus
fluctuations in the variable above or below the set point, detected by a receptor "sensor"
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response
a physiological activity that helps return the variable to the set point
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thermoregulation
the process by which animals maintain an internal temperature within a normal range
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endothermic
warmed mostly by heat generated by metabolism
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ectothermic
gain most of their heat from external sources
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countercurrent exchange
the transfer of heat (or solutes) between fluids that are flowing in opposite directions
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hypothalamus
the brain region where the sensors for thermoregulation are concentrated
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endocrine system
signaling molecules released into the bloodstream by endocrine cells are carried to all locations in the body
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hormones
the signaling molecules broadcast throughout the body by the endocrine system
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pancreas
A gland located behind the stomach; stimulated by the hormone secretin into the blood stream, responds by releasing bicarbonate into ducts leading to the duodenum
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pituitary gland
located at the base of the hypothalamus; where signals from hypo travel; two parts
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anterior pituitary
hormonal signals from the hypothalamus trigger the synthesis and release of hormones from this
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posterior pituitary
an extension of the hypothalamus; stores and releases two hormones: Oxytocin and ADH
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oxytocin
a hormone that regulates milk release during nursing in mammals as part of the neuroendocrine pathway
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Vasopressin (ADH)
Antidiuretic hormone: promotes retention of eater by kidneys; influences social behavior and bonding
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positive feedback
reinforces a stimulus, leading to an even greater response
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epinephrine
also called adrenaline; secreted by adrenal glands; raises blood glucose levels, increases blood flow to muscles, decreases blood flow to digestive system
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osmoregulation
the general term for the processes by which animals control solute concentrations in the interstitial fluid and balance water gain and loss
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excretion
the process that rids the body of nitrogenous metabolites and other metabolic waste products
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osmolarity
total solute concentration expressed as molarity; moles of solute per liter of solution
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osmoconformer
to be isoosmotic with surroundings; all are marine animals
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osmoregulator
to control internal osmolarity independent of the environment
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ammonia
a small, toxic molecule produced by nitrogen fixation or as a metabolic waste product of protein and nucleic acid metabolism
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urea
a soluble nitrogenous waste produced in the liver by a metabolic cycle that combines ammonia with carbon dioxide
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uric acid
a product of protein and purine metabolism and the major nitrogenous waste product of insects, land snails, and many reptiles. Uric acid is relatively non-toxic and largely insoluble
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transport epithelia
one or more layers of epithelial cells specialized for moving particular solutes in controlled amounts in specific directions
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filtrate
water and small solutes, such as salts, sugars, amino acids, and nitrogenous wastes, cross the membrane, forming a solution called this
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selective reabsorption
recovers useful molecules and water form the filtrate and returns them to the body fluids
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selective secretion
non-essential solutes and wastes are left in the filtrate or added to it by this
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kidney
a specialized organ which functions in both osmoregulation and excretion
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ureter
duct through which urine produced by each kidney exits
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urethra
tube through which during urination urine is expelled from the bladder
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nephrons
functional units of the vertebrate kidney
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Bowman's capsule
cup-shaped swelling which surrounds the glomerulus (ball of capillaries)
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protonephridia
earliest type of excretory system (flatworms); flame bulbs grab things from fluid; tons and tons of waste holes, all separate
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malpighian tubules
waste gets thrown into digestive system; food waste and nitrogenous waste come out together
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proximal tubule
reabsorption is critical for the recapture of ions, water, and valuable nutrients from initial filtrate; NaCl enters, water follows by osmosis
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descending limb of loop of Henle
reabsorption of water continues; freely permeable to water; passive transport
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ascending limb of loop of Henle
salt moves out of nephron; active transport
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distal tubule
regulates K+ and NaCl concentrations
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collecting duct
carries the filtrate through the medulla to the renal pelvis
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countercurrent multiplier
expends energy to create a concentration gradient; going in opposite directions causes something to happen
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essential nutrients
materials that an animal cannot assemble from simpler organic precursors
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essential fatty acids
animals cannot synthesize; contain one or more double bonds
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essential amino acids
humans require 8, babies 9
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vitamins
organic molecules that are required in the diet in very small amounts
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minerals
inorganic nutrients that are usually required in small amounts
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undernutrition
a diet that fails to provide adequate sources of chemical energy
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malnutrition
a failure to obtain adequate nutrition
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ingestion
the act of eating or feeding
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digestion
the second stage of food processing; food is broken down into molecules small enough for the body to absorb
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mechanical digestion
breaks food into smaller pieces; increasing the surface area for chemical processes
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chemical digestion
necessary because animal cannot directly use proteins, carbs, nucleic acids, fats, and phospholipids in food
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absorption
the animal's cells take up small molecules
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elimination
undigested material passes out of the digestive system
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gastrovascular cavity
pouch which functions in digestion as well as the distribution of nutrients throughout the body
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alimentary canal
complete digestive tract; two openings
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peristalsis
alternating waves of contraction and relaxation; how food moves down the alimentary canal
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sphincters
ringlike valves in the muscular layer of some junctions between specialized compartments
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salivary glands
deliver saliva through ducts to the oral cavity
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amylase
hydrolyzes starch and glycogen into smaller polysaccharides and the disaccharide maltose
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mucus
a viscous mixture of water, salts, cells, and slippery glycoproteins
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bolus
the ball into which the tongue shapes the food before swallowing
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esophagus
connects to the stomach
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stomach
stores food and begins digestion of proteins
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gastric juice
stomach secretes the components of a digestive fluid called this
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chyme
mixture of ingested food and digestive juice
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protease
protein-digesting enzyme; ex. pepsin
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pepsin
breaks peptide bonds and cleaves proteins
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small intestine
enzymatic hydrolysis of macromolecules from food occurs; longest compartment
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duodenum
first 25 cm of small intestine; where chyme mixes with digestive juices from the pancreas, liver, and gallbladder
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pancreas
aids chemical digestion by producing an alkaline solution rich in bicarbonate as well as several enzymes
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bile
a mixture of substances made in the liver; contains bile salts which act as emulsifiers that aid in digestion and absorption of lipids
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gallbladder
where bile is store and concentrated
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villi
finger-like projections lining the lining of the small intestine
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hepatic portal vein
blood vessel that leads directly to the liver
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large intestine
includes colon, cecum, rectum
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cecum
important for fermenting ingested material, especially in animals that eat large amounts of plant material
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appendix
finger-like extension of the human cecum, has a minor and dispensable role in immunity
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feces
wastes of the digestive system
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rectum
where feces are stored until they can be eliminated; there are two sphincters, inner involuntary, outer voluntary
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crop
stores food in other animals
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gizzard
stores and mechanically digests food in other animals
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bioenergetics
the flow and transformation of energy in an animal
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metabolic rate
animal's energy rate per unit of time
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diabetes mellitus
disease caused by deficiency of insulin or a decreased response to insulin in target cells
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open circulatory system
the circulatory fluid is also the interstitial fluid; arthropods and some molluscs like clams
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hemolymph
circulatory fluid in an open system
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closed circulatory system
blood is confined to vessels and is distinct from the interstitial fluid
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cardiovascular system
closed circulatory system of humans and other vertebrates
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arteries
carry blood from the heart to the organs throughout the body
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capillaries
microscopic vessels with very thin, porous walls
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capillary beds
networks of capillaries
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veins
the vessels that carry blood back to the heart
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atria
the chambers that receive blood entering the heart
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ventricles
the chambers responsible for pumping blood out of the heart
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single circulation
the blood passes through the heart once in each complete circuit; bony fishes, rays, and sharks
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double circulation
circulatory system with two circuits; amphibians, reptiles, mammals
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gas exchange circuit
where there is a net movement of O2 into the blood and CO2 out of the blood
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pulmonary circuit
gas exchange where capillary beds involved are the lungs
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pulmocutaneous circuit
gas exchange where capillaries are in both lungs and skin (amphibians)
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systemic circuit
the branch of the circulatory system that supplies oxygenated blood to and carries deoxygenated blood away from organs and tissues throughout the body
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cardiac cycle
one complete sequence of pumping and filling
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systole
contraction phase of the cardiac cycle
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diastole
relaxation phase of the cardiac cycle
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atrioventricular valve
lies between each atrium and ventricle
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semilunar valves
located at the two exits of the heart
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sinoatrial node
pacemaker; sets the rate and timing at which all other cardiac muscles contract
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atrioventricular node
where impulses are delayed so that the atria can empty completely before the ventricles contract
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electrocardiogram (EKG)
current against time of SA node
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pulse
the rhythmic bulging of the artery walls with each heartbeat
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vasoconstriction
as the smooth muscles in the arteriole walls contract the arterioles narrow, process called this
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vasodilation
when the smooth muscles of the arterioles relax; an increase in diameter which causes blood pressure to decrease
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lymphatic system
includes a network of tiny vessels intermingled among capillaries of the cardiovascular system; lost fluid and proteins return to the blood via this
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lymph
fluid lost by capillaries; composition same as interstitial fluid
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lymph nodes
filter lymph and house cells that attack viruses and bacteria
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plasma
liquid matrix in which cells are suspended in blood
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platelets
cell fragments that are involved in the clotting process
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stem cells
multipotent and dedicated to replenishing the body's blood cell populations
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hemoglobin
the iron-containing protein that transports O2
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leukocytes
white blood cells
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thrombus
clot formed within a blood vessel that blocks the flow of blood
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LDL
delivers cholesterol to cells for membrane production
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HDL
scavenges excess cholesterol for return to the liver
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atherosclerosis
hardening of the arteries by fatty deposits
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heart attack
myocardial infarction; damage or death of cardiac muscle tissue resulting from blockage of one or more coronary arteries
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stroke
death of nervous tissue to the brain due to a lack of O2
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hypertension
high blood pressure
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partial pressure
the pressure exerted by a particular gas in a mixture of gases
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skin as a respiratory organ
dense network of capillaries facilitates the exchange of gases between the circulatory system and the environment
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gills
outfoldings of the body surface that are suspended in the water
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ventilation
movement of the respiratory medium over the respiratory surface
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tracheal system
network of air tubes that branch throughout the body
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lungs
localized respiratory organs
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larynx
upper part of the respiratory tract
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bronchi
the trachea branches into two of these
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alveoli
air sacs clustered at the tips of the tiniest bronchioles
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surfactant
a material that reduces surface tension
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breathing
the alternating inhalation and exhalation of air
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positive pressure breathing
filling the lungs with forced airflow
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negative pressure breathing
pulling, rather than pushing, air into the lungs
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diaphragm
a sheet of skeletal muscle that forms the bottom layer wall of the cavity
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tidal volume
the volume of air inhaled and exhaled with each breath
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vital capacity
tidal volume during maximal inhalation and exhalation
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residual volume
the air that remains after a forced exhalation
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respiratory pigments
circulate with the blood or hemolymph and are often contained within specialized cells; they greatly increase the amount of O2 that can be carried in the circulatory fluid
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lysozyme
an enzyme that breaks down bacterial cell walls, acts as a chemical barrier against pathogens ingested with food
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Neutrophils
white blood cells; are attracted by signals from infected tissues
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macrophages
white blood cells; larger phagocytic cells
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natural killer cells
circulate through the body and detect the abnormal array of surface proteins characteristic of some virus-infected and cancerous cells
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interferons
proteins that provide innate defense by interfering with viral infections
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complement system
proteins circulate in an inactive state and are activated by substances on the surface of many microbes
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inflammatory response
the changes brought about by signaling molecules released upon injury or infection
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lymphocytes
white blood cells; T and B cells
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thymus
an organ in the thoracic cavity above the heart
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T cells
lymphocytes which migrate from the bone marrow to the thymus
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B cells
lymphocytes that remain and mature in the bone marrow
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antigen
any substance that elicits a response from a B cell or T cell
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antigen receptor
protein to which the B cell or T cell binds to an antigen
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epitope
the small, accessible portion of an antigen that binds to an antigen receptor
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effector cells
actually go out and do battle
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memory cells
what makes you acquired; doesn't do anything now--but later remembers
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