Monoamine oxidase inhibitors

  1. What is the indication for MAOIs?
    Atypical depression
  2. What is the MOA?
    Inhibition of enzymes that break down catecholamines - MOA-A and MOA-B
  3. What are the adverse effects of MOAIs?
    Hypertension
  4. What are the contraindications for MOAIs?
    General anesthesia within 10days

    Elective surgery within 10days

    Congestive heart failure
  5. Special considerations?
    Discontinuation of MOAIs before new therapy begins

    Avoid food with tyramine (cheese, wines, yeast products)

    Should not be taken if patient is taking ephedrine, amphetamine, methylphenidate, levodopa or meperidine
  6. Name 3 MOAIs
    Phenelzine

    Selegiline

    Tranylcypromine
  7. BN for phenelzine?
    Nardil
  8. BN for selegiline?
    Eldepryl
  9. BN for tranylcypromine?
    Parnate
  10. GN for Nardil?
    phenelzine
  11. GN for Eldepryl
    selegiline
  12. GN for Parnate?
    Tranylcypromine
Author
Fari052
ID
267791
Card Set
Monoamine oxidase inhibitors
Description
For atypical depression
Updated