Card Set Information
GH is used in the management of growth failure in
due to what?
chronic renal insufficiency
What is GH used to manage (mostly in adults)?
short stature associated with Turners syndrome
Short bowel syndrome
What drug is used for underproduction of GH?
Adverse effects of Somatropin.
Hyperglycemia & insulin resistance
Edema of hands/feet
H/A & HTN initially but resolve
Contraindications of GH.
children w/ epiphiseal closure
caution w/ severe renal & hepatic disease
Drug given for overproduction of GH.
Adverse rxns of Ocreotide.
immediate yellowing of skin or sclera
Contraindications of Ocreotide.
caution w/ renal impairment or failure
liver & cardiac disease
What does Ocreotide do in addition to the natural hormone?
suppresses stomach bleeding and GI secretions
Most common cause of hypothyroidism.
What two facters characterize hypothyroidism?
1. hypometabolic state
2. myxedematous changes in body
What is myxedema?
An extreme complication of hypOthyroidism.
a mucous type of edema caused by an accumulation of fatty substances in CT
Characteristics of hypometabolic state.
gradual onset of weakness & fatigue
wt gain & decreased appetite
GI motility slowing = constipation
mental dullness, decreased memory, slow reflexes
Myxedematous changes in the body.
mechanism of axn for Levothyroxine.
increases metabolic rate
The key in dosing Levothyroxine.
"low & slow"
Med for hypothyroidism.
Most common cause of hyperthyroidism.
Most visible signs of hyperthyroidism.
Three classes of steroids.
Mineralocorticoids (Aldosterone 95%)
Things to report with corticosteroid drugs.
wt gain > 1 kg in 24 hrs or >2kg in a week
What side effects would you see with corticosteroid use due to increased fluid retention?
Dosing for hydrocortisone.
: 10-320 mg/day, 3-4 divided doses
: 15-800 mg/day, 3-4 divided doses
max = 2g/day
Adverse effects of LONG-term corticosteroid use.
suppresses immune system = increased risk for infection
peptic ulcers (esp w/ NSAIDS)
nervousness, moodiness, hallucinations
cataracts & glaucoma
Adverse effects of vasopressin.
necrosis & gangrene
What is vasopressin used to treat?
central or neurogenic DI (IM or SQ)
alternative to epinephrine (IV)
esophageal or upper GI bleeding
severe hypotension or shock