Hormones (Pharm 2)

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Author:
MeganM
ID:
268735
Filename:
Hormones (Pharm 2)
Updated:
2014-04-01 10:00:25
Tags:
Hormones
Folders:
TAMHSC
Description:
Pharm 2
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  1. Action of Somatropin
    • tgts muscle & bone
    • stim increase in cell size & #
    • brks down adipose
  2. Adverse effects of Somatropin.
    • HYPERGLYCEMIA/insulin resistance
    • joint pain/muscle aches
    • rapid initial gain, then slows
    • early- edema in hands/feet
    • initial-H/A & HTN, then resolves
  3. What should you monitor with Somatropin?
    • changes in gait 
    • knee and hip pain
    • (could mean avascular necrosis)
  4. Uses of Ocreotide.
    • overproduction of GH
    • decreases GI secretions & abdominal bleeding
  5. Adverse effects of Ocreotide.
    • GI systems
    • increased LFTs
    • immediate yellowing of skin & sclera
    • RUQ pain
  6. Teaching points for Ocreotide.
    • Take b/w meals & HS
    • rotate injection sites
    • reconstitute gently
    • do not shake 
    • bring to rm temp B4 injection
    • (monitor vitamin B-12, EKG, BGL, hepatic & renal)
  7. Contraindications for Ocreotide.
    • renal impairment or failure
    • liver & heart disease
    • DM 
    • HypOthyroidism
  8. Indications for Desmopressin.
    • neurogenic DI (decreased ADH)
    • nocturnal enuresis
    • controls polyuria & polydipsia
  9. Adverse effects of Desmopressin.
    • Water intox
    • nasal congestion/rhinitis
    • anaphylaxis (IV)
    • *hypotension or HTN
    • *dysrhythmias/angina
  10. Drug interactions with Desmopressin.
    • increased axn with NSAIDS
    • decreased axn with heparin, epi, alcohol
  11. How to treat an OD of Desmopressin?
    diuretics
  12. Contraindications of Desmopressin.
    • nephrogenic DI
    • can worsen renal impairment (fluid)
    • caution - CAD, HTN, risk for hyponatremia or thrombi

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