15.1 Mood Disorders
Card Set Information
15.1 Mood Disorders
kalat psych 261
State of feeling sad, helpless, and lacking in energy and pleasure for weeks at a time.
Low levels of BDNF (brain-derived neurotrophic factor)
Depression after giving birth
Drugs that prevent the presynaptic synapses that release serotonin and catecholamine molecules from reabsorbing them.
Prolongs the presence of neurotransmitters in the synaptic cleft
Causes drowsiness, dry mouth, heart irregularities, difficulty peeing.
Selective serotonin reuptake inhibitors
Drugs that block the reuptake of serotonin into the presynaptic terminal
Monoamine oxidase inhibitors
Block MAO, a presynaptic terminal enzyme that metabolizes serotonin and catecholamines into inactive forms
So the presynaptic terminal has more neurotransmitters available for release
Miscellaneous antidepressants with mild side effects
Electrically inducing a convulsion in an attempt to relieve depression or other disorder
Increases proliferation of neurons in the hippocampus, responsiveness to exercise
Condition in which a patient alternates between depression and mania (restless activity, self-confidence, excitement, rambling speech, loss of inhibitions).
Lithium and anticonvulsant drugs
Stabilizes mood in bipolar patients
Decrease glutamate activity
Blocks synthesis of arachidonic acid, synthesized during brain inflammation
Seasonal affective disorder
Are phase-delayed unlike patients with other forms of depression
: light affecting serotonin synapses and altering circadian rhythms
Unawareness of stimuli to which a person did not direct their attention
Burst of stimuli leaving a synapse potentiated for long periods of time
Specificity - only the most active synapse is strengthened
Cooperativity - nearly simultaneous stimulation by two or more axons produce much more LTP
Associativity - pairing a weak input with a strong input enhances later response to the weak input
Glutamate receptor that also responds to AMPA
When massively stimulated by glutamate, the AMPA receptor allows nearby NMDA receptors to be stimulated by glutamate also.
Glutamate receptor that also responds to NMDA
When stimulated, allows calcium to enter the cell, which sets into motion a series of reactions that potentiate the dendrite's future responsiveness to glutamate at AMPA receptors.