PHARM 3 Seizures & Muscle Spasms
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What is used to diagnose Myasthenia Gravis?
What is used for treatment for Myasthenia Gravis?
Route of administration for Reganol?
PO, at bedtime, but can be given IM if unable to swallow
What is Sinemet?
Combination of Levadopa & Carbidopa
What kind of food should you not eat with Levadopa or Siminet and why?
protein, b/c it will bind with the protein
How long does it take for a pt to experience the full therapeutic effects of Sinemet?
may teke several months
Two things to remember when a person is having a seizure.
- Nothing in the mouth
- Protect the head
What to administer in an O.D. of Diazepam (Valium)?
Diazepam is not normally given to _____, especially with _____ problems. Why?
- kidney problems
- they get very agitated
Most serious side effect of diazepam.
What to assess for with diazepam.
- (all precursors to cardiovascular collapse)
What is diazepam used for?
Increases the seizure threshold (seizure treatment)
Mech of axn for diazepam.
- Enhances axn of GABA in brain,
- inhibits abnormal neuronal discharges
What color urine will the use of phytoin produce
Uses of Dilantin.
Prophylactic therapy of all types of seizures EXCEPT absence seizures
Adverse effects of Dilantin.
- Can be very toxic
- CNS effects common (lethargy, drowsiness, headache, dizziness)
What can high doses of Dilantin cause?
- ***GINGIVAL HYPERPLASIA**
What drug can cause gingival hyperplasia?
What must be monitored in pts taking Dilantin?
BGL b/c it may inhibit insulin release
What should you assess for and report immediately in pts taking Dilantin? Why?
- sore throat, bruising, nosebleeds
- may indicate a blood dyscrasia
Therapeutic range of Dilantin.
What is carbamezepine (Tegretol) used for?
- treatment and maintenance of seizures
- NOT for active seizures
Mechanism of axn for Tegretol.
inhibits Na+ channels, blocking the repetetive, sustained firing of neurons
OD treatment for Tegretol.
Activated charcoal & gastric lavage
When should you notify HCP in pts taking Tegretol?
Do not take Tegretol with _________.
OD treatment for Depakote.
An important teaching point with Dilantin.
brush and floss teeth several times a day (2-3 times) to prevent gingival hyperplasia
Common muscle spasm meds.
Uses of Valium.
- pain relief & discomfort from musculoskeletal disorders
- management of anxiety
- acute alcohol w/d
- tetanus treatment
30 mcg/mL of _____ may result in a coma.
When are muscle spasm meds contraindicated?
Children under 12
Side effects of muscle spasm meds.
CNS (dizziness, weakness, drowsiness)
AE of muscle spasm meds.
- Angioedema, anaphylaxis
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