PHARM 3 Seizures & Muscle Spasms

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PHARM 3 Seizures & Muscle Spasms
2014-04-19 18:59:50
Pharm 3
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  1. What is used to diagnose Myasthenia Gravis?
  2. What is used for treatment for Myasthenia Gravis?
  3. Route of administration for Reganol?
    PO, at bedtime, but can be given IM if unable to swallow
  4. What is Sinemet?
    Combination of Levadopa & Carbidopa
  5. What kind of food should you not eat with Levadopa or Siminet and why?
    protein, b/c it will bind with the protein
  6. How long does it take for a pt to experience the full therapeutic effects of Sinemet?
    may teke several months
  7. Two things to remember when a person is having a seizure.
    • Nothing in the mouth
    • Protect the head
  8. What to administer in an O.D. of Diazepam (Valium)?
    Flumazenil (Romazicon)
  9. Diazepam is not normally given to _____, especially with _____ problems. Why?
    • elderly
    • kidney problems
    • they get very agitated
  10. Most serious side effect of diazepam.
    cardiovascular collapse
  11. What to assess for with diazepam.
    • hypotension
    • tachycardia
    • edema
    • (all precursors to cardiovascular collapse)
  12. What is diazepam used for?
    Increases the seizure threshold (seizure treatment)
  13. Mech of axn for diazepam.
    • Enhances axn of GABA in brain,
    • inhibits abnormal neuronal discharges
  14. What color urine will the use of phytoin produce
  15. Uses of Dilantin.
    Prophylactic therapy of all types of seizures EXCEPT absence seizures
  16. Adverse effects of Dilantin.
    • Can be very toxic 
    • CNS effects common (lethargy, drowsiness, headache, dizziness)
  17. What can high doses of Dilantin cause?
    • nystagmus
    • confusion
    • ataxia
    • coma
    • seizures
  18. What drug can cause gingival hyperplasia?
  19. What must be monitored in pts taking Dilantin?
    BGL b/c it may inhibit insulin release
  20. What should you assess for and report immediately in pts taking Dilantin? Why?
    • sore throat, bruising, nosebleeds
    • may indicate a blood dyscrasia
  21. Therapeutic range of Dilantin.
    10-20 mcg/mL
  22. What is carbamezepine (Tegretol) used for?
    • treatment and maintenance of seizures
    • NOT for active seizures
  23. Mechanism of axn for Tegretol.
    inhibits Na+ channels, blocking the repetetive, sustained firing of neurons
  24. OD treatment for Tegretol.
    Activated charcoal & gastric lavage
  25. When should you notify HCP in pts taking Tegretol?
    rash (SJS)
  26. Do not take Tegretol with _________.
    grapefruit juice
  27. OD treatment for Depakote.
  28. An important teaching point with Dilantin.
    brush and floss teeth several times a day (2-3 times) to prevent gingival hyperplasia
  29. Common muscle spasm meds.
    • Soma
    • Flexeril
    • Valium
  30. Uses of Valium.
    • pain relief & discomfort from musculoskeletal disorders
    • management of anxiety
    • acute alcohol w/d
    • tetanus treatment
    • antieptileptic
  31. 30 mcg/mL of _____ may result in a coma.
  32. When are muscle spasm meds contraindicated?
    Children under 12
  33. Side effects of muscle spasm meds.
    CNS (dizziness, weakness, drowsiness)
  34. AE of muscle spasm meds.
    • SJS
    • Angioedema, anaphylaxis
    • dysrhythmias
    • seizures