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Unit 5
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B Cells
Produce antibodies
made in the bone marrow
finds antigens, clones its self, then squirts out antibodies
T cells
made in bone marrow
trained in the thymus
grabs onto the foreign antigen
does not squirt out antibodies
Antigens
cause the body to produce antibodies or highly specialized T cells
1st level immune response
skin
mucus membranes
non specific
2nd level immune response
protien
cell wall based responses
non specific
3rd level immune response
B and T cells
Specific
antibodies
immunoglobulins
IgG
The most of
cross walls of blood vessels and enter tissue
in breast milk and placenta
indicative of a previous exposure to an antigen
IgM
The biggest
first to appear
remain in blood-do not enter surrounding tissue
indicative of current exposure to an antigen
IgA
Found in body secretions
to prevent the attachement of pathogens
IgE
high levels of alleric reaction or gastrointestinal parasite
Primary response
initial contact
no detectable antibodies for several days
slow rise in titer
Secondary response
memory or anamnestic
this is the response after second exposure
it is more rapid and intense because of the memory B cells from the primary response
mouse antibodies
monoclonal antibodies
Active immunity
exposure to a foreign antigen results in production of antibodies
Passive immunity
antibodies are transferred from one organism to another
Naturally acquired active immunity
Developed during life
chicken pox
Naturally acquired passive immunity
From mother to infant
Artificially Acquire active immunity
Vaccination
giving your body the actual disease but a version that can't hurt you so you body makes it's own antibodies
artificially acquired passive immunity
injection of antibodies into the body
short lived 2 to 3 months
attenuated
viable-alive-but harmless
MMR
mumps
measles
rubella
DTP
diphtheria
tetanus
Partessus
Herd Immunity
if everyone has it the few who can't get the vaccine are fine
Hemolytic disease of the newborn
Mother is Rh neg
Baby is RH positive because of RH positive father
cyclosporine
given to transplant patients to keep their bodies from rejecting the organ
pregnancy tests work because of
HCG
AIDS
Acquired Immunodeficiency syndrome
HIV
Human Immunodeficiency virus
Type 1 hypersensitivity reactions
Body should send IgM but sends IgE
like bees or wasps or hay fever or allergies
antibodies
Type 2 hypersensitivity reactions
from transfusions
cytotoxic
antibodies
Type 3 hypersensitivity reactions
small clumps of antigens and antibodies that settle into the basement membrane and cause inflammation
antibodies
Type 4 hypersensitivity reactions
TB and poison ivy
T cells
phenotype
gram stains
genotypic methods
chlamydia
Nisseria gonorrhea
have to use PCR to increase amount of DNA
Titer
concentration of serum antibodies
ELISA
Enzyme Linked Immunosorbent Assay
Author
NurseJoy
ID
270069
Card Set
Unit 5
Description
Unit 5
Updated
4/10/2014, 8:46:38 PM
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