BRAND/GENERIC - Depression

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Author:
Rgirlx14
ID:
270959
Filename:
BRAND/GENERIC - Depression
Updated:
2014-04-21 16:42:47
Tags:
im too cool
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Description:
ch. 48
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  1. fluoxetine
    • Prozac, Sarafem, Prozac Weekly
    • SSRI
    • sexual side effects
    • longest half life - 5 week washout
  2. fluoxetine + olanzapine
    • Symbyax
    • SSRI + atypical antipsychotic - resistant depression (QHS)
  3. paroxetine
    • Paxil, Pexeva, Paxil CR, Brisdelle (x)
    • SSRI
  4. fluvoxamine
    • Luvox, Luvox CR
    • SSRI
  5. sertraline
    • Zoloft
    • SSRI
    • top choice for cardiac patients
  6. citalopram
    • Celexa
    • SSRI
    • QT risk >40 mg/day or >20 mg/day if 60+ years, liver dx, 2C19 issues
    • not in children, avoid if cardiac risk
  7. escitalopram
    • Lexapro (s form)
    • SSRI
    • QT risk >20 mg/day, do not exceed 10 mg/day in elderly
  8. vilazodone
    • Viibryd
    • SSRI + 5HT1A¬†partial agonist
    • With Food, Less sexual SEs
  9. vortioxetine
    • Brintellex
    • SSRI + 5HT3, 5HT7, receptor antagonist, 5HT1A¬†agonist, partial 5HT1B agonist
  10. venlafaxine
    • Effexor, Effexor XR
    • SNRI - Depression, GAD
    • increase BP
  11. duloxetine
    • Cymbalta
    • SNRI - Depression, peripheral neuropathy (pain), fibromyalgia, GAD, chronic low back pain, chronic osteoarthritis pain
    • increase BP
  12. desvenlafaxine
    • Pristiq
    • SNRI - Depression
    • increase BP
  13. levomilnacipran
    • Fetzima
    • SNRI - Depression
    • increase BP
  14. amitriptyline
    • Elavil
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • tertiary amine
  15. doxepin
    • Zonalon (pruritis), Silenor (insomnia)
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • tertiary amine
  16. clomipramine
    • Anafranil
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • tertiary amine
  17. imipramine
    • Tofranil, Trofranil PM (not interchangeable)
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • tertiary amine
  18. trimipramine
    • Surmontil
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • tertiary amine
  19. amoxapine
    • -
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • secondary amine
  20. desipramine
    • Norpramine
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • secondary amine
  21. Maprotiline
    • -
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • secondary amine
  22. Nortriptyline
    • Pamelor
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • secondary amine
  23. protriptyline
    • Vivactil
    • tricyclic - NE, 5HT reuptake inhibitors; ACh, histamine blockers
    • secondary amine
  24. isocarboxazid
    • Marplan
    • MAOI
  25. phenelzine
    • Nardil
    • MAOI
  26. tranylcypromine
    • Parnate
    • MAOI
  27. selegiline transdermal patch
    • Ensam
    • MAOI B selective inhibitor
  28. bupropion
    • Aplenzin, Budeprion SR, Budeprion XL, Wellbutrin SR, Wellbutrin XL, Wellbutrin, Forfivo XL
    • DA and NE reuptake inhibitor
  29. mirtazapine
    • Remeron, Remeron SolTab
    • inhibits 5HT reuptake; alpha1-adrenergic and histamine blocker
    • sedation, increase appetite, weight gain
  30. aripiprazole
    • Abilify, Abilify Discmelt
    • antipsychotic - treatment resistance depression only
  31. olanzapine + fluoxetine
    • Symbyax
    • antipsychotic - treatment resistance depression only
  32. quetiapine extended-release
    • Seroquel, Seroquel XR
    • antipsychotic - treatment resistance depression only

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