PT VI

Card Set Information

Author:
alvo2234
ID:
271017
Filename:
PT VI
Updated:
2014-04-18 17:32:20
Tags:
PK
Folders:
Exam III
Description:
Felder
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  1. OCs increase the plasma lvs of which drugs
    • NSAIDs
    • BZDs
    • antiseizure
    • CCS
    • Caffeine
    • Theophylline
    • modafinil
    • antifungal
    • rifampin
  2. which drugs should be considered to find an alt with OCs
    • antiseizure
    • CNS (modafinil)
    • antifungal
    • rifampin
  3. recommendations for NSAIDs and OCs
    chech K lvs
  4. recommendation for CCS and OCs
    decrease dose of CCS
  5. recommendation for BZD and OCs
    decrease BZD dose
  6. what is the plasma increase of thyophelline when taken with OC
    30%
  7. what is the percentage inc/decr when alprazolam is taken with OCs
    decrease clearance by 22% and increase t1/2 by 58%
  8. cyclosporine and OCs inhibits which liver enzymes
    cyp450
  9. OCs may decrease the effectiveness of which agents
    • warfarin
    • insulin
    • OHAs
  10. how does phenytoin, barbiturates, and carbamazepine affect OCs
    • increase metabolism of OCs
    • pregnancy or breakthrough bleeding may result
  11. what effect does modafinil have on OCs
    decreases ethinyl estradiol concentration by 11% but has no effect on the half-life
  12. how does rifampin affect OC metabolism
    increases estrogen metabolism
  13. what is levonorgestrel and what is the dose
    morning after pill; 1.5 mg
  14. what happens if a pt vomits < 2 hrs after taking levonorgestrel
    give another dose
  15. levonorgestrel intrauterine device
    mirena
  16. what should be done if a pt taking oral levonorgestrel has severe vomiting
    the pt should consider vaginal administration of the oral tablet
  17. which order of kinetics is levonorgestrel
    zero order

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