Ch 18 Blood 5

Card Set Information

Author:
eddardofwinter
ID:
271294
Filename:
Ch 18 Blood 5
Updated:
2014-04-20 22:48:27
Tags:
Bio
Folders:
School
Description:
slides
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user eddardofwinter on FreezingBlue Flashcards. What would you like to do?


  1. —low WBC count: below 5,000 WBCs/mL
    –Causes: radiation, poisons, infectious disease
    –Effects: elevated risk of infection
    Leukopenia
  2. —high WBC count: above 10,000 WBCs/mL
     –Causes: infection, allergy, disease
    Leukocytosis
  3. —cancer of hemopoietic tissue that
    usually produces an extraordinary high number of circulating leukocytes and
    their precursors
    Leukemia
  4. What are the four kinds of leukemia? What are teh effects?
    • Myeloid leukemia: uncontrolled granulocyte production
    • Lymphoid leukemia: uncontrolled lymphocyte or monocyte production
    • Acute leukemia: appears suddenly, progresses rapidly, death within months
    • Chronic leukemia: undetected for months, survival time 3 years
    •    –Effects: normal cell percentages disrupted; impaired clotting; opportunistic infections
  5. —the cessation of bleeding
       –Stopping potentially fatal leaks
       –Hemorrhage: excessive bleeding
    Hemostasis
  6. •Three hemostatic mechanisms
    • –Vascular spasm
    • –Platelet plug formation
    • –Blood clotting (coagulation)
  7. —small fragments of megakaryocyte cells
    Platelets
  8. –Stem cells (that develop receptors for thrombopoietin) become megakaryoblasts
    •Thrombopoiesis
  9. –Repeatedly replicate DNA without
    dividing
    –Form gigantic cells called
    megakaryocytes with a multilobed nucleus
       •100 mm in diameter, remains in bone
         marrow
    •Megakaryoblasts
  10. —live in bone marrow adjacent to blood sinusoids
    –Long tendrils of cytoplasm (proplatelets)
    protrude into the blood sinusoids: blood flow splits off fragments called
    platelets
    –Circulate freely for 10 days
    –40% are stored in spleen
    Megakaryocytes
  11. •Clot retraction occurs within __ minutes
    30
  12. —dissolution of a clot
       –Factor XII speeds up formation of kallikrein      enzyme
       –Kallikrein converts plasminogen
       into plasmin, a fibrin-dissolving enzyme that      breaks up the clot
    Fibrinolysis
  13. —abnormal clotting in unbroken vessel
    Thrombosis
  14. –clot
     •Most likely to occur in leg veins
      of inactive people
    Thrombus
  15. –clot may break free, travel from veins to lungs
    Pulmonary embolism
  16. —anything that can travel in the blood and block blood vessels
    Embolus
  17. (tissue death) may occur if clot blocks blood supply to an organ (MI or stroke)
    –650,000 Americans die annually of
    thromboembolism (traveling blood clots)
    Infarction

What would you like to do?

Home > Flashcards > Print Preview