bio

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what are the two methods of transport of oxygen

dissolved O2 and bound to Hb
what method is in plasma ~1.5%

dissolved O2
what method is bound to iron in center of heme, 98.5% carried this way, "oxyhemoglobin"

boung to Hb
what % of heme units that contain O2 at any given moment

hemoglobin saturation
what is a very small change in the Po2 results in big change in the ability of Hb to bind O2 (or release O2)

steep slope
what are the two factors which affect how much O2 binds to Hb

Ph and temperature
when there is and increase curve "shifts" left Hb wants to release less O2

Ph
when there is a decrease curve "shifts" right Hb wants to release more O2

pH
20C decrease Hb release less O2

temperature
40C increase Hb release more O2

temperature
what by product of glycolysis (make ATP) reaction in RBC's,

BPG production
increase BPG = increase release of O2 by Hb

BPG production
what is a by product of aerobic metabolism in peripheral tissues

CO2
what are the methods of CO2 transport

carbonic acid 70% , bound to globular protein subunits of Hb 23%, dissolved in plasma 7%
what is in red blood cells, CO2—> carbonic anhydrase —> carbonic acid (H2CO3) —> H+(hydrogen ion) plus HCO3- (bicarbonate ion)

carbonic acid
what has carbaminohemoglobin (HbCO2)

bound to globular protein subunits of Hb

Author

271572

Card Set

bio

Description

study

Updated

2014-04-23T04:06:57Z

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