test 3

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test 3
2014-04-29 10:05:30
test 3
test 3
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  1. IgM
    • First antibody produced during primary response¬†
    • Pentamer molecule¬†
    • Large size, so it stays in the blood
  2. IgG
    • provides longest term protection
    • Generally first in secondary response
    • monomer
    • transported to fetus, and protects it for 6 months
    • found in colostrum
  3. IgA
    • mostly a dimer
    • most abundant Ig class
    • produced by MALT tissue
    • important in mucosal immunity
    • found in secretions
  4. IgD
    role in devleopment and maturation of immune response
  5. IgE
    • barely detectable in blood
    • most of it is bound to basophils and mast cells
    • deals with allergies
  6. What occurs during neutralization?
    prevents toxins and viruses from attaching to cell surface
  7. What occurs during opsonization?
    Phagocytosis is easier and more efficient
  8. What is the complement system activation?
    activation of complement system which leads to opsonization, inflammation, and formation of MACs and cell lysis
  9. What occurs during immobilization and prevention of adherence?
    prevents bacteria from entering host
  10. What occurs during agglutination?
    antibodies can bind to different bacteria simultaneously, making phagocytosis easier
  11. What occurs during antibody-dependent cellular cytotoxicity?
    antibodies bind to large pathogen so NK cells bind to Fc portion of antibody and cause cell lysis
  12. What is mutualism?
    When both partners benefit from a relationship
  13. What is commensalism?
    when one partner benefits and the other is unharmed
  14. What is parasitism?
    When one partner benefits at the others expense
  15. What are resident microbiota?
    microbes that inhabit the body for extended periods
  16. What are transient microbiota?
    Microbes that inhabit the body temporarily
  17. What are the 3 protective roles of microbiota?
    • covering binding sites
    • using available nutrients
    • produce compounds toxic to pathogens
  18. What is colonization
    establishment of the microbe on a body's surface
  19. What is subclinical?
    when there are no or mild symptoms
  20. What is infections disease?
    pathogen causes noticeable effects
  21. What is the difference between signs and symptoms
    symptoms are subjective and signs are objective evidence
  22. What does virulent mean?
    refers to degree of pathogenicit
  23. What are virulence factors?
    traits that allow the microorganisms to cause disease
  24. What are communicable or contagious disease?
    diseases that are easily spread
  25. What is the course of an infectious disease?
    • Incubation period-time between infection and onset of symptoms
    • prodromal period-mild signs and symptoms
    • illness-signs and symptoms of diseas
    • convalescence- recuperation
  26. What are acute infections?
    symptoms develop quickly and last for a short time
  27. What are chronic infections?
    develop slowly and last months or years
  28. What are latent infections?
    never completely eliminated
  29. What is a localized infection?
    microbes limited to a small area
  30. What is a systemic infection?
    agents are spread throughout the body
  31. What does -emia mean>
    in the blood