HESI Pharm

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  1. Doxorubicin (Adriamycin) is specifically known for its __________.
  2. Saquinavir (Invirase)
    • Avoid sun
    • take WITH meals
    • take with high-calorie, high-FAT meals
  3. Ketoconazole (antifungal).
    • avoid alcohol
    • WITH food
    • avoid antacids 2 hrs after
    • avoid sun
  4. Nevirapine (Viramune), a NRTI for HIV AE.
    • rash
    • SJS
    • hepatitis
    • increased transaminase levels
  5. clozapine (Clozaril) for schizophrenia, what lab study to monitor for AE?
    • WBC - check before & monitor closely
    • also monitor for agranulocytosis (sore throat, malaise, fever)
  6. Why is Disulfiram (Antabuse) used?
    • adjunct treatment for pts w/ chronic alcoholism
    • *must abstain from alcohol for AT LEAST 12 hrs prior to initial dose
  7. What's the big AE with -"rubricin" drugs (chemo)?
  8. "-mycin" drugs major AE (chemo drugs)
    pulmonary fibrosis (not as hard on heart)
  9. AE of Prozac
    CNS & GI dysfunctions
  10. Normal range of Lithium.
  11. What's the major AE of Vincristine (chemo drug)?
    • NEUROtoxicity
    • (double vision, vocal cord paralysis, etc)
    • -may take several months to appear and to resolve
  12. Texanes ("taxel") most common AE
    • hypersensitivity rxn
    • *ALWAYS premedicated with something like dexamethasone, diphenhydramine, H2 blocker ("tidine")
  13. Increased doses (>450mg) of Wellbutrin commonly causes what?
    seizure activity
  14. Important teaching for sulfisoxazole.
    • High fluid intake, take w/ full glass of H20
    • some will turn urine dk brown or red
  15. Long-term use of hydroxyurea (Hydrea) causes?
    Secondary leukemias
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HESI Pharm
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