Workman 18-19 review.txt

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Author:
wdgassett
ID:
272606
Filename:
Workman 18-19 review.txt
Updated:
2014-04-30 22:38:54
Tags:
respiratory nausea vomiting etc
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Description:
Workman Understanding Pharmacology chapters 18-19
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  1. What do cholinergic antagonists (anticholinergic drugs) do for respiratory problems?
    Anticholinergc drugs block the parasympathetic nervous system (which restores HR and airway diameter to resting levels) allowing natural epinephrine and norepinephrine to bind to smooth muscle receptors; bronchodilation results.
  2. What kind of drug is albuterol (Proventil)?
    Short-acting beta2 agonists (SABA) Bronchodilator
  3. What kind of drug is salmeterol (Serevent)?
    Long-acting beta2-agonists (LABA)
  4. How do mucolytic drugs improve airflow?
    Mucolytics improve airflow by reducing the thickness of mucus in the airways.
  5. Name a phenothiazine drug:
    promethazine (Phenergan)
  6. How do phenothiazine drugs work?
    • Phenothiazines block dopamine receptors in the chemotrigger zone of the brain inhibiting one or more vomiting reflex pathways.
    • The sedating effects help control sensation of nausea.
  7. What kind of drug is scopolamine (L-hyoscine)?
    Anticholinergic drug used as antiemetic. They stop intestinal cramping and inhibit vestibular input (balance and position) into the CNS
  8. How does ondansetron (Zofran) work?
    A 5HT3-receptor antagonists that binds to and blocks serotonin receptors in the intestinal tract and the chemotrigger zone of the brain, two pathways of vomiting reflex.
  9. What is bisacodyl (Dulcolax)?
    Stimulant drug for constipation.
  10. What are common side effects of bisacodyl (Dulcolax)?
    • abdominal cramps
    • diarrhea
    • hypokalemia
    • muscle weakness
    • nausea
    • rectal burning
  11. What is bismuth subsalicylate (Pepto-Bismol) used for?
    Antidiarrheal drugs
  12. What are side effects of bismuth subsalicylate (Pepto-Bismol)?
    • constipation
    • gray-black stools
    • impaction in infants and debilitated patients
    • tinnitus
  13. Should bismuth subsalicylate (Pepto-Bismol) be given to children under 16?
    NO; it contains an aspirin-like drug.

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