Workman 24-25 review.txt

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Author:
wdgassett
ID:
272608
Filename:
Workman 24-25 review.txt
Updated:
2014-04-30 22:40:56
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Endocrine Diabetes
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Description:
Workman Understanding Pharmacology chapters 24-25
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  1. Signs and Symptoms of Hyperthyroidism
    • General Symptoms
    • Diarrhea
    • Difficulty sleeping
    • Feeling too warm most of the time
    • Fine tremors of the hands
    • Heartbeat irregularities
    • High blood pressure
    • Higher than normal body temperature
    • Menstrual irregularities
    • Rapid HR
    • Sweating
    • Thinning of scalp hair
    • Weight loss
  2. Additional symptoms specific to Graves ’ disease only:
    • Blurred vision
    • Bulging or protruding eyes (exophthalmia)
  3. levothyroxine (Synthroid) is what kind of drug?
    a thyroid hormone replacement drug
  4. methimazole (Tapazole) is what kind of drug?
    thyroid-suppressing drug
  5. How does methimazole affect warfarin?
    Thyroid-suppressing drugs enhance the action of warfarin, increasing risk for excessive bruising and bleeding.
  6. What is the action of glucagon?
    Glucagon prevents hypoglycemia by raising blood glucose levels back up to normal.
  7. What is an adverse effect of metformin (Glucophage XR)?
    Metformin can cause lactic acidosis.
  8. How does metformin work?
    Metformin acts on the liver to reduce the release of glucose from stored glycogen. They also increase the sensitivity of the insulin receptor to the binding of naturally secreted insulin, thus improving the movement of glucose from the blood into the cells
  9. What are side effects of rosiglitazone (Avandia)?
    Side effects of thiazolidinediones are upper respiratory infections, headaches, muscle aches, fluid retention, weight gain, and anemia.
  10. How does Avandia work?
    Thiazolidinedione drugs (or glitazones) work with the patient’s own insulin to reduce blood glucose levels by making the insulin receptor more sensitive to insulin.
  11. Name rapid acting insulin:
    • lispro (Humalog)
    • aspart (NovoLog)
    • glulisine (Apidra)
    • clear
  12. Rapid acting insulin onset, peak, duration:
    • lispro (Humalog)
    • aspart (NovoLog)
    • glulisine (Apidra)
    • clear
    • onset: 10-30 min.
    • peak: 30 min – 3 hours
    • duration: 3-5 hours
  13. Short acting insulin onset, peak, duration:
    • Regular (Humulin R, Novolin R)
    • clear
    • onset: 30 min. – 1 hour
    • peak: 2 – 5 hours
    • duration: 5 – 8 hours
  14. Intermediate acting insulin onset, peak, duration:
    • NPH (Humulin N, Novolin N)
    • cloudy
    • onset: 1.5 – 4 hours
    • peak: 4 – 12 hours
    • duration: 12 – 18 hours
  15. Long acting insulin onset, peak, duration:
    • glargine (Lantus)
    • detemir (Levemir)
    • clear
    • onset: .8 – 4 hours
    • peak: no pronounced peak
    • duration: 24 + hours
  16. What insulin cannot be mixed with other insulin?
    Neither Lantus nor Levemir can be mixed with other insulin.

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