Chapter 22-3

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  1. Important precursors for pyrimidine:
    orotate
  2. The source of nitrogen needed to make nucleotides:
    Glutamate and Aspartate (recall roles for Glu in amino acid synthesis and Asp in urea cycle).
  3. Sources of the atoms in the purine rings:
    Aspartate, glycine (2 carbons from glycine), formate, CO2, and amide of glutamine.
  4. Specific products of purine synthesis:
    Fumarate and lots of ADP
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272633
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Chapter 22-3
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22-3
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