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sedative hypnotic drugs
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what do sedative hypnotic drugs do?
drugs the depress the CNS function
primarily used to treat anxiety and insomnia
types of sedative drugs
benzodiazepnes
benzodiazepine like drugs
barbiturates
what do Benzodiazepines do?
used to treat insomnia and anxiety
used to induce general anesthesia
used to manage seizure disorders
What is benzodiazepines potential for abuse?
LOW potential for abuse
What should you not mix with benzodiazepines?
alcohol (you can stop breathing)
Pharmacologic effects on which systems of Benzodiazepines?
CNS
cardiovascular system
respiratory system
Therapeutic uses
anxiety
insomnia
seizure disorders
muscle spasm
alcohol withdrawal
panic disorder
perioperative applications
adverse effects to Benzodiazepines
too much CNS depression
anterograde amnesia
sleep driving
paradoxical effects
respiratory depression
abuse
Can you develop dependence on Benzodiazepines?
yes, but incidence of dependence is low
Can you become tolerant to Benzodiazepines?
yes, you can become tolerant to some effects but not others
What reverses the effects of Benzodiazepines?
flumazenil
Types of Benzodiazepine like drugs
zolpidem, Zaleplon, Eszopiclone
what is Ramelteon?
a melatonin agonist
what does ramelteon do?
it activates melatonin receptors
What is ramelteon used for?
approved fro chronic insomnia
also dramatically reduces delirium
Three classifications of Barbiturates
ultrashort acting
short to intermediated acting
long acting
Mechanism of action of Barbiturates
binds to the GABA receptor chloride channel complex
Pharmacologic effects of Barbiturates
CNS depression
Cardiovascular effects
Induction of hepatic drug metabolizing enzymes
Types of tolerance with Barbiturates
develops tolerance to many of CNS effects
does not develop tolerance to respiratory depression
therapeutic uses of barbiturates
seizure disorders
induction of anesthesia
insomnia
adverse effects of barbiturates
respiratory depression
suicide
abuse
use in pregnancy
exacerbation of intermittent porphyria
hangover
paradoxical excitement
hyperalgesia
how do you remove Barbiturates from the body?
no way---> you have to just let the body flush it out by itself
Author
kimiko
ID
272646
Card Set
sedative hypnotic drugs
Description
sedative
Updated
5/1/2014, 6:46:53 AM
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