Integrase Inhibitors

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Author:
jtkd4192
ID:
273170
Filename:
Integrase Inhibitors
Updated:
2014-05-05 01:05:07
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Integrase Inhibitors
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Description:
Integrase Inhibitors
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  1. Generic: raltegravir (RAL)
    -DO NOT administer with polyvalent ions (Mg2+, Ca2+, Fe2+/3+)

    -no P450 interxns
  2. Generic: elvitegravir
    -co-administered w/ StribildĀ® (TDF+FTC+cobicistat)


    -take with food
  3. Generic: dolutegravir
    oral BA increases w/ food

    UGT1A1 metabolism

    Toxicities: dyslipidemia, increased LFT, hypersx.

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