Card Set Information
What kingdom incorporates mycology?
Two groups in Kingdom Fungi
: Molds and yeasts
How do fungi obtain food?
They are heterotrophic
Possibly parasites living on the tissues of other organisms
Growth temp for fungi
20-40 degrees celcius
Where are fungi present?
Air, Dust, Fomites and normal flora
Are fungi normally pathogenic or non pathogenic?
Only 300 species(100,000 total) have been linked to diseases in animals
What causes human Mycoses?
True fungal pathogens and opportunistic pathogens
Fungal pathogen can invade and grow in a health noncompromised host
Ability to grow as different structures
Grow as molds at 30 Celsius and yeast at 37 celsius
Adapting to host by switching from hyphal cells to yeast cells is an example of what?
What are the 3 portals of entry for fungi
Primary mycoses- Respiratory portal; inhaled
Subcutaneous- inoculated skin; trauma
Cutaneous and superficial- contamination on skin surface
Virulence Factors of fungi
capsules and adhesion factos
What are some human defense mechanisms against pathogens?
Antifungal defenses are the integrity of the barriers and resp. cilia
: Cell mediated immunity(phagocytosis) and inflammation
Long term immunity does not occur in most cases
Is immunization effective or non effective for mycotic infections?
Usually not effective
Some control agents of mycotic infections are what?
Amphotericin B, Flucytosine, Azoles, nystatin
In some cases surgical removal of damaged tissues
5 types of mycoses
3 types of systemic mycoses
Histoplasmosis (ohio valley)
Coccidioidomycosis (valley fever)
Deep tissue/Lung pathogens
May also involve multi organ infection
Healthy people may also become infected
Histoplasma Capsulatum (about, transmission, treatment)
Most common true pathogen
: Bird poop -> mold -> spores -> lungs -> multiple organs(immunocompromised)
: Amphotericin B/ ketoconazole
Blastomyces dermatitidis (about, transmission, treatment)
Can cause chronic cutaneous, bone, and CNS complications
: Inhaled spores from mold in soil
: Amphotericin B
Coccidioides immitis (about, transmission, treatment)
Causes coccidioidomycosis (valley fever)
Found in ALKALINE soils in southwest US
: same as histo
: Amphotericin B
Subdermal/ deep tissue infection but reamins localized
Causes sporotrichosis (rose-gardeners disease)
Very common that decomposes plany matter in soil
Infect appendages and lungs
: When contaminated plat matter penetrates the skin and the pathogen forms a nodules then spreads to LYMPH NODES
Infects the skin or finger nails
Infections strictly confined to keratinized epidermis (skin, nails, scalp)
AKA ringworm or tinea
: Natural reservoirs (humans animals and soil); Public showers, swimming areas
Long infection period followed by localized inflammation and allergic reactions
Ringworm of the scalp
Ringworm of the body
Ringworm of the groin
Ringworm of the nails
Ringworm of the foot/hand
Treatment of dermatophytoses
Topical antifungal agents