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What are the ejection phase indices?
The non-ejection phase indices?
CO, SV, EF
Peak pos Dp/Dt, acceleration time
What shifts the starling curve downward and to the right?
Increased afterload or decreased contractility (reduced myocardial performance)
What shifts the Starling curve up and to the right?
Decreased afterload or increased contractility (increased myocardial performance)
What does a force-tension curve show?
Relationship of afterload and stroke volume
What shifts the force-tension curve up?
Left on the line?
Right on the line?
Increased contractility or increased preload
Decreased contractility or decreased preload
What does the pressure/volume graph show?
Preload, afterload, and contractility
What does the upper left corner of the pressure/volume curve represent?
The bottom right?
What does the top of the loop represent?
End-systolic pressure and Afterload
End diastolic pressure and Preload
Stroke volume and contractility
What does beta 1 do?
Increase heart rate and contractility (cardiac specific)
Decrease afterload (dilate skeletal muscles)
Increase afterload and preload (constrict arteries and veins)
What is the most potent vasodilator?
What determines afterload?
Arterioles to the skeletal muscles
What drug is an alpha agonist?
beta 1 and beta 2?
What drug is helpful for a patient with HCM and hypotension?
What drug is the drug of choice for stimulating outflow tract gradient in HCM?
What is the physiological difference between high dose and low dose epinephrine?
low dose beta 2 > alpha in the skeletal muscles
high dose alpha > beta 2 (BP goes way up)
What does prazosin do?
selective alpha 1 blocker
What does labetalol block?
alpha, beta 1, beta 2