seizure drugs

Card Set Information

Author:
baseball4life189
ID:
275044
Filename:
seizure drugs
Updated:
2014-05-22 00:02:42
Tags:
seizure
Folders:

Description:
seizures
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user baseball4life189 on FreezingBlue Flashcards. What would you like to do?


  1. Luminal
    • phenobarbital
    • level: 15-40 mcg/mL
    • Induces 2C9/19 and 3A4
  2. Mysoline
    • Primidone
    • level: 5-12 mcg/mL
    • Induces 2C9/19 and 3A4
    • Metabolite: phenobarb, phenylethylmalonamide (toxic)
  3. Dilantin
    • Phenytoin
    • level: 10-20 mcg/mL
    • 50mg/min push
    • CI:┬ásinus brady, sino-atrial block, 2nd or 3rd degree AV block, Adams-Stokes syndrome
    • dilute in NS only
    • Gingival hyperplasia
    • Toxicity: nystagmus, loss of taste, hypotension, rash
  4. Cerebyx
    • Fosphenytoin
    • Refrigerate
    • CI: sinus brady, sino-atrial block, 2nd or 3rd degree AV block, Adams-Stokes syndrome
  5. Peganone
    • Ethotoin
    • PO
    • No antiarrhythmic properties
    • Less effective/toxic than phenytoin
  6. Mesantoin
    • Mephenytoin
    • PO
    • Antiarrhythmic
    • Fatal blood dyscrasias
  7. Valium (tab/soln/IV)
    Diastat (rectal gel)
    • Diazepam
    • Status epilepticus
    • ADR: resp. depression, dizziness, droawsiness, anterograde amnesia
  8. Klonopin
    • Clonazepam
    • PO/ODT wafers
    • concomitant use with VPA may produce absence status
    • ADR: salivation, inc. libido, palpitation, confusion
  9. Tranxene
    • Clorazepate
    • PO/PO SR
    • ADR: drowsiness, ataxia, memory impairment, confusion
  10. Onfi
    • Clobazam
    • Lennox-gastaut
    • Dose adjust to 5mg/day if poor 2C19 metabolizer; titrate to 10-20mg/day
    • Pregnancy category C
  11. Tegretol (tab, susp)
    Epitol (tab)
    • Carbamazepine
    • DOC in trigeminal neuralgia
    • Levels: 4-12 mcg/mL
    • metabolized to 10,11-epoxide (toxic)
    • Autoinducer of 3A4; watch for oral contraceptives
    • BBW: aplastic anemia, agran, toxic epidermal necrolysis, SJS
  12. Depakene
    • Valproic acid cap/suspension
    • Level: 50-100 mcg/mL
    • BBW: hepatotoxicity, teratogenicity (possible autism), decreased IQ, pancreatitis
  13. Depakote
    • Divalproex DR, EC tab, sprinkles
    • Level: 50-100 mcg/mL
    • BBW: hepatotoxicity, teratogenicity (possible autism), decreased IQ, pancreatitis
  14. Depacon
    • Valproic acid Injection
    • Level: 50-100 mcg/mL
    • BBW: hepatotoxicity, teratogenicity (possible autism), decreased IQ, pancreatitis
  15. Stavzor
    • Valproic DR capsules
    • Level: 50-100 mcg/mL
    • BBW: hepatotoxicity, teratogenicity (possible autism), decreased IQ, pancreatitis
  16. Felbatol
    • Felbamate
    • Refractory epilepsy only due to fatal aplastic anemia
    • acute hepatic failure
  17. Neurontin
    • Gabapentin
    • separate from antacids
  18. Gralise
    • gabapentin
    • postherpetic neuralgia
  19. Horizant
    Gabapentin enacarbil for restless leg syndrome
  20. Lamictal
    • Lamotrigine
    • PO and ODT
    • can cause SJS, titrate slowly
  21. Gabitril
    • Tiagabine
    • BBW: patients without epilepsy having seizures should not use tiagabine
  22. Topamax
    • Topiramate
    • Tabs or sprinkle caps
    • ADR: weight loss, kidney stones (increase fluid), decreases bicarb (since it's a carbonic anhydrase inhibitor)
    • Can be used for migraine headache prophylaxis
  23. Qudexy
    • Topiramate
    • Extended release caps
  24. Trileptal
    Oxtellar extended release
    • oxcarbazepine
    • hyponatremia
  25. Zonegran
    • Zonisamide
    • watch out for hypersensivity
    • increase water intake (kidney stones)
  26. Keppra
    Keppra XR
    • Levetiracetam
    • NOT metabolized by cyp nor induces or inhibits
    • Requires renal adjustment
  27. Lyrica
    • Pregabalin
    • NOT metabolized by cyp nor induces or inhibits
    • C-V drug
  28. Banzel
    • Rufinamide
    • shortens the QT interval
    • NOT metabolized by cyp
    • weakly inhibits 2E1, induces 3A4
  29. Vimpat
    • Lacosamide
    • Caution with known cardiac conduction problems, myocardial ischemia, or heart failure
    • C-V drug
  30. Sabril
    • Vigabatrin
    • "sabertooth claws eyes out"
    • Only for refractory epilepsy infantile spasms
    • BBW: progressive and permanent bilateral concentric visual field constriction
  31. Potiga
    • Ezogabine
    • "it's easy to get pot"
    • REMS drug
    • BBW: Retinal abnormalities
    • Caution: QTc prolongation
  32. Fycompa
    • Perampanel
    • BBW: serious or life threatening psych or behavioral reactions (aggression, hostility, irritability, etc)
  33. Aptiom
    • Eslicarbazine
    • CI: similar to oxcarbazepine, so do not use in hypersensitivity in oxcarbazepine or carbamezapine
  34. Zarontin
    • Ethosuximide
    • DOC in absence seizures
    • levels: 40-100 mcg/mL
    • MAY precipitate tonic-clonic seizures
  35. Celontin Kapseals
    • Methsuximide
    • does NOT precipitate tonic-clonic seizures

What would you like to do?

Home > Flashcards > Print Preview