bone tumors

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  1. what are bone tumors classified as ?
    • Primary or metastatic
    • Primary can either be benign or malignant
  2. how do you work up tumor?
    • Age 
    • Location
    • Symptomatology
  3. what type of lytic bone destruction will one notice with tumors?
    • A. Geographic
    • 1 Least aggressive pattern
    • 2 Indicative of slow growing lesion
    • 3 Uniquely well defined sclerotic margin that is separated from surrounding bone
    • 4 Usually benign lesions such as giant cell tumors,bone cysts,and enchondromas
    • 5 Short zone of transition from tumor changes to regular bone

    • B. Moth­Eaten
    • Lacks a definitive shape
    • Faster growth than geographic pattern which indicates malignancy
    • Seen more commonly in cancellous bone
    • Multiple small lesions lacking definitive shape
    • These lesions have less well­ defined sclerotic margins
    • Long zone of transition from abnormal to normal bone
    • indicative of malignant tumors and OM

    • C. Permeative
    • Usually seen in cortical bone
    • Aggressive lesions with very rapid growth potential suggesting malignancy
    • Less well­ defined margins not easily separated from surrounding normal bone
    • May be imperceptibly merged with uninvolved segment
    • Long zone of transition from abnormal to normal bone
    • indicative of malignant bone tumors
  4. Name few Lytic bone lesions?
    • F - fibrous dysplasia or fibrous cortical defect
    • O - osteoblastoma
    • G - giant cell tumour
    • M - metastasis(es)
    • A - aneurysmal bone cyst
    • C - chondroblastoma or chondromyxoid fibroma
    • H - hyperparathyroidism (brown tumour)
    • I - infection (osteomyelitis)
    • N - non-ossifying fibroma
    • E - enchondroma or eosinophilic granuloma
    • S - simple (unicameral) bone cyst
  5. Match trabecular patterns
    • Giant Cell Tumor ­ -delicate, thin 
    • Chondromyxoid Fibroma ­ -coarse, thick 
    • Aneurysmal Bone Cyst ­ -delicate, horizontal
    • Non­ossifying Fibroma/Fibrous -Cortical Defect ­ lobulated "soap bubble" appearance
    • Hemangioma ­-striated, radiating
  6. match periosteal reactions
    One layer of periosteum laid down against and separated from cortex -solitary bone cyst

    Multiple layers of periosteum -osteosarcoma (osteogenic sarcoma), Ewing's

    Radiating spicules (starburst) ­-osteosarcoma

    Hair on end radiating spicules ­-Ewing's sarcoma

    Triangular elevation of periosteum ­-Codman's triangle
  7. match position of lesion
    • Central: Within the medullary canal
    • Enchondroma, solitary bone cyst, and fibrous dysplasia

    • Eccentric: Arising from one side of the central axis of the bone
    • Giant cell tumor, osteosarcoma, chondrosarcoma, fibrosarcoma, chondromyxoid
    • fibroma
    • Cortical: Arising in or near the cortex
    • Non­ossifying fibroma, osteoid osteoma

    • Periosteal: Arising within the periosteum
    • Periosteal sarcoma, osteochondroma
  8. most common source of metastatic tumors? 
    most common benign primary bone tumor?
    most common malignant primary bone tumor?
    what is definitive diagnosis?
    • -breast, lung, prostate, kidney and multiple myeloma
    • -Osteochondroma
    • -Multiple myeloma
    • -Biopsy
  9. what are tumors of diaphyseal bone?
    • Ewing's Sarcoma
    • Multiple Myeloma
    • Osteoid Osteoma
    • Osteoblastoma
    • Fibrous Dysplasia
    • Fibrosarcoma
    • Eosinophilic granuloma
  10. what are the tumors of metaphyseal bone?
    • Osteosarcoma
    • Enchondroma
    • Solitary (Unicameral) Bone Cyst
    • Aneurysmal Bone Cyst
    • Osteochondroma
    • Chondrosarcoma
    • Non­Ossifying fibroma
    • Chondromyxoid Fibroma
    • Giant Cell Tumor (Children before plate closure)
  11. what are the tumors of Epiphyseal bone?
    • Chondroblastoma
    • Intraosseous Ganglion
    • Hemangioma
    • Giant Cell Tumor (Adults after plate closure)
Card Set:
bone tumors
2014-05-28 01:10:22
bone tumors

bone tumors
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