Acute, painful axillary nodes on the ipsilateral hand (same side as the cat scratch)
How do you diagnose Cat Scratch Disease?
Positive hanger-rose test (not used today b/c you infect a person with the material from a diseased individual and see if there is a positive result)
negative results for other causes of the lymphadenopathy
histologic presence of lymphnode changes, especially in the presence of pleomorphic bacteria B. henselae IDed with warthin-starry stain
direct flourescent-antibody test for B. henselae
What is the treatment for Cat scratch disease?
Self-limiting, resolution within 4 months
if ill, children can take: gentamycin, oral trimethoprim sulfamethoxazole, rifampin
if ill, adults take ciprofloxin
In HIV pts: erythromycin, doxycycline, or combination isoniazid, rifampin and ethambutol
What is bacillary angiomatosis?
A non-neoplastic condition presenting with little knots of capillaries in various organs caused by the same bacteria as cat scratch disease: Bartonella henselae
What are characteristcs of Bacillary angiomatosis?
1. caused by bartonella henselae (same as cat scratch disease)
2. common in HIV infection
What is the treatment of Bacillus bartonella henselae?
- A combination of isoniazid, rifampin, and ethambutol
How do you detect bacillary angiomatosis?
It is a non-neoplastic condition presenting with little knots of capillaries in various organs and can be detected with a silver stain - warthin-starry stain. Black stains indicates a positive result for the etiological agent (bartonella henselae).