Infections in pregnancy

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Author:
trincam2008
ID:
276458
Filename:
Infections in pregnancy
Updated:
2014-06-09 15:34:08
Tags:
infections
Folders:
O&G
Description:
Infections in pregnancy
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  1. Cytomegalovirus - CMV
    1. Path
    2. Foetal/neonatal effects: asymp and symp at birth
    3. Diagnosis
    4. Mx
    1. Herpes virus, requires personal contact. Common cause of childhood handicap and deafness.

    • 2. Vertical transmission - 40%
    • - 10% symptomatic at birth: IGUR, pneumonia and thrombocytopenia; severe neurological sequela e.g. hearing, visual and mental impairment. 
    • - asymptomatic at risk of deafness

    • 3. - Ultrasound abnormalities: intracranial and hepatic calcification in only 20%
    • - Maternal infections is confirmed, amniocentesis at least 6/52 after maternal infection -> confirm or refute vert trans

    • 4. - Most infected neonates are not seriously affected
    • - Close surveillance for US abnormalities and fetal blood sampling at 32/40 for fetal platelet levels - determine those at most risk
    • - no prenatal treatment
    • - no routine treatment, no vaccinations
  2. Infections suitable for screening: 3 certain, 3 probably
    • Syphilis
    • Hep B
    • Rubella
    • (SHebR)

    • Probably:
    • - Chlamydia
    • - Bacteria vaginosis
    • - beta-haemolytic streptococcus
    • (BBC)
  3. Tetatogenic infections
    • - CMV (cytomegalovirus)
    • - Rubella
    • - Toxoplasmosis
    • - Syphilis
    • - Herpes Zoster
    • (con rua to nhu meo so hai)

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