UTI and Anti-fungal Meds

Sulfinamides- bactruim

Antiseptic agents- decrease bacterial growth

Urinary Analgesic- helps to reduce

Other agents- Peni, cephral, aminoglycides, fluroquinolones,

• most common agent is bactrium
• combo drug- Sulfamethoxazole and trimenthoprim)

Broad spectrum

MOA- block folic acid and then u can't make RNA and DNA unable to replicate

two drugs block the formation of folic acid in two different places

most common SE hypersensitivity- rash pt turns bright pink, photsensitivity, anemia, crystaluria- crystal in urine- forms when urine is more acidic u want this to more alkaline (push fluids) also NA bicard tabs , nephrotox.

• NI: bun.creatin- sunscreen, admins 1 hr before or 2 hrs after admin to decrease GI upset
• dont give with antacid

Ex- Macrodantin 

CI local effect in the urine

MOA- block the enzyme needed for Carborhydrates so the cell doesn;t have any energy and it dies. blocks energy source

Broad spectrum- acute or reoccurence UTI

SE: GI-, peripheral neuropathy, superinfection, hypersensitivity 

• NI: admin with food decrease upset
• change urine to brown
• suprainfection

Ex: Pyridium

CI: local in urinary tract

MOA- unknown

it is well tolerated

Urine bright orange-to red colors

used to reduce pain no antimoribial

alter cell permeability, allows cell contents to fall out

• local effect
• topical- on the skin

• in the mouth- swish and spit
• in throat- swish and swallow (in esophagus)

works best on contact. the longer u keep it in the mouth it works

SE: few

NI swish

Esophaheal/oropharnyngeal infections

mouth and throat - not being cleared with Nystatin

Specturm wide- can be used for systemic infection

SE- GI, increase liver enzyme, and renal function 

NI: take with food and monitor renal and liver function

antifugal agents

• drug of choice for severe systemic fungal infections (life threatening) 
• SE: nephrotoxic, renal function watch, 
• IV low slowly pump- monitor for 15 mins- pt present with a fever, chills, headache

• pretreat them to decrease the sign of allergy ie benadryl 
• assess CBC
• BUN/creatinine