Glaucoma drugs NBEO.txt

Card Set Information

Author:
cjensen20
ID:
277173
Filename:
Glaucoma drugs NBEO.txt
Updated:
2015-07-15 10:05:44
Tags:
ophthalmic glaucoma NBEO
Folders:

Description:
NBEO glaucoma drugs
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user cjensen20 on FreezingBlue Flashcards. What would you like to do?


  1. What prostaglandins are there (name brand)?
    • Xalatan
    • Lumigan
    • Travatan
    • Travatan P
  2. What are the generic prostaglandins?
    • Lumigan = bimatoprost
    • Travatan Z = travoprost
    • Xalatan = latanoprost
  3. What are the major side effects of prostaglandins?
    • Eyelash growth
    • Hyperemia
    • Iris pigment change
    • Dark skin around eye
    • Compromised orbital fat
  4. What prostaglandin causes itching?
    Lumigan = bimatoprost
  5. What are contraindications of prostaglandins?
    • Active uveitis
    • CME
    • HSV keratitis
  6. What percentage IOP decrease is expected in prostaglandins?
    30-35%
  7. What is the mode of action of prostaglandins?
    Increasing uveoscleral outflow by pulling on CB and thus causing less resistance
  8. What color lid are prostaglandins?
    aqua
  9. What b-blockers are there?
    • Betagan
    • Betopic-S
    • Carteolol
    • Istalol (Timoptic, Betimol, Timoptic preservative free,Timoptic-XE)
  10. What are the generic b-blockers?
    • Betagan = levobunolol hydrochloride
    • Betimol = timolol hemihydrate
    • Betoptic-S = betaxolol hydrochloride
    • Istalol and all Timoptics = timolol maleate
  11. What are major side effects of b-blockers?
    • Sinus bradycardia
    • Heart problems
    • Severe asthma
    • Impotence
  12. What b-blocker is b-1 specific?
    Betoptic =betaxolol
  13. What percentage IOP decrease is expected in b-blockers?
    25%
  14. What combo drugs include b-blockers?
    • Cosopt (Trusopt/dorzolamide & timolol)
    • Combigan (Alphagan/brimonidine & timolol)
  15. What color lid are b-blockers?
    blue or yellow
  16. What is the mode of action of b-blockers?
    • Decrease aqueous production
    • Increases trabecular outflow
  17. Why are there different concentration of beta-blockers?
    • 0.25% for Caucasian patients
    • 0.50% for darker patients
    • Melanin pigments tend to bind to beta-blocker molecules, so in the end both patients receive about 0.25%
  18. What brand-name carbonic anhydrase inhibitors are there?
    • Azopt
    • Trusopt
    • Cosopt (combo drug)
    • Diamox(oral)
    • Neptazane (oral)
    • Methazolamide (oral)
    • Dichlorphenamide (oral)
  19. What are the generic CAIs?
    • Azopt = brinzolamide
    • Trusopt = dorzolamide
    • Cosopt = Trusopt/dorzolamide & timolol
    • Diamox = acetazolamide
  20. What color lid are CAIs?
    Orange
  21. What is the mode of action of CAIs?
    • Reduces biocarbonate
    • Prevents aqueous production
  22. What glaucoma medication class is sulfa based?
    CAIs
  23. What percentage IOP decrease is expected in CAIs?
    18%
  24. What are major side effects of CAIs?
    • Bone marrow suppression
    • Myopia
    • Diuresis
    • Bitter taste
    • GI upset
    • Aplastic anemia
  25. What are contraindications of use of CAIs?
    • Dialysis and kidney disease
    • SJS
    • If corneal edema is present
  26. What is the mode of action of alpha (a2) adrenergics?
    Decrease production and increase outflow by constricting CB
  27. What brand-name alpha (a2) adrenergic agonists are there?
    • Alphagan
    • Alphagan P
    • Iopidine
    • Combigan
    • Simbrinza
  28. What are the generic alpha adrenergics?
    • Alphagan = brimonidine
    • Iopidine = apraclonidine
    • Combigan = Alphagan/brimonidine & timolol
    • Simbrinza = Alphagan/brimonidine & azopt/brinzolamide)
  29. What glaucoma medication class is safest in preggers?
    Alpha (a2) adrenergics
  30. What color lid are alpha (a2) adrenergics?
    purple or white
  31. What drug class can be used in active uveitis?
    Alpha (a2) adrenergics
  32. What are major side effects of alpha (a2) adrenergics?
    • Dry mouth
    • Periocular blepharitis / dermatitis
  33. What percentage IOP decrease is expected in alpha (a2) adrenergics?
    • 18% for Alphagan
    • 30% for apraclonidine
  34. What glaucoma medication is also used to diagnosis horner’s syndrome (as an alternative to cocaine)?
    Apraclonidine
  35. What combo drugs are there for glaucoma?
    • Simbrinza (brimonidine / brinzolamide)
    • Combigan (brimonidine / timolol)
    • Cosopt (dorzolamide / timolol)
  36. What docosanoids are there?
    Rescula (unoprostone isopropyl)
  37. How much IOP is decreased with docosanoids?
    3-4mm Hg
  38. What cholinergic agonists are there?
    Pilocarpine
  39. What glaucoma drug is used to diagnosis adies tonic pupil?
    Pilocarpine 0.125%
  40. What are major side effects of cholinergic agonists?
    • SJS
    • Bone marrow depression
    • Kidney problems
  41. What classes of drugs are contraindicated for cases of active uveitis?
    • Prostaglandins
    • Cholinergic agonists

What would you like to do?

Home > Flashcards > Print Preview