Brand and generics

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Brand and generics
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2014-06-30 22:24:15
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Pharmacy study guide
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  1. Brintellex
    vortioxetine


    SSRI, 5HT3/HT1D/HT7 antagonist, 5HT1A agonist, and 5HT1B partial agonist

    NO sexual side effects
  2. Viibryd
    vilazodone

    SSRI and 5HT1A partial agonist

    LESS sexual side effects
  3. Primaxin
    imipenem/cilostatin
  4. Moxatag
    amoxicillin
  5. Tequin
    gatifloxacin
  6. Diprovan
    propofol
  7. Lotensin
    benazepril
  8. Inspra
    eplerenone
  9. Demadex
    torsemide

    loop diuretic
  10. Edecrin
    etacrynic acid

    loop diuretic

    no sulfa components
  11. Doans
    salicylate
  12. Kayexelate
    sodium polystyrene sulfonate (SPS)

    Used in hyperkalemia
  13. Jalyn
    tamsulosin + dutasteride
  14. Hytrin
    terazosin

    non-selective alpha blocker used in BPH and rarely HTN
  15. Minipress
    prazosin

    non-selective alpha blocker used in BPH and rarely HTN
  16. Avodart
    dutasteride
  17. Proscar
    finasteride
  18. Brisdelle
    paroxetine ER

    Used for hot flashes in menopause
  19. Cardura
    dozasosin

    non-selective alpha blocker used in BPH and rarely HTN
  20. Uroxatral
    alfuzosin

    selective alpha blocker used in BPH
  21. Fanapt
    iloperidone

    atypical antipsychotic
  22. Rapaflo
    silodosin

    selective alpha blocker used in BPH
  23. Sensipar
    cinacalcet
  24. Zemplar
    paricalcitol

    Treats hyperparathyroidism in CKD patients
  25. Imuran
    azathioprine
  26. Vesicare
    solifenacin
  27. Toviaz
    fesoterodine
  28. Enablex
    darifenacin
  29. Sanctura
    trospium
  30. Cycloset
    bromocriptine

    dopamine agonist used for Type 2 DM
  31. Kombiglyze
    metformin + saxagliptin
  32. Jentadueto
    metformin + linagliptan
  33. Kazano
    alogliptin + metformin
  34. Treximet
    sumatriptan + naproxen
  35. Lysteda
    tranexamic acid

    used to treat heavy menstrual bleeding
  36. Diamox
    acetazolamide

    carbonic anhydrase inhibitor - used to treat altitude sickness
  37. Atarax / Vistaril
    hydroxyzine
  38. Buspar
    buspirone

    5HT1 partial agonist

    preg. cat. B
  39. Zarontin
    ethosuximide

    absence seizures
  40. Zonegran
    zonisamide

    anticonvulsant

    sulfa drug!
  41. Equetro
    carbamazepine

    for bipolar disorder
  42. Felbatol
    felbamate

    used for refractory seizures

    AEs: hepatic failure, aplastic anemia
  43. Aptiom
    eslicarbazepine

    anti-convulsant
  44. Potiga
    ezogabine

    Used for refractory seizures; CV

    AEs: blue skin discoloration, vision changes, urine color changes
  45. Vimpat
    lacosamide

    anticonvulsant; CV

    AEs: cardiac
  46. Banzel
    rufinamide

    Used for Lennox-Gastaut seizures

    AEs: QT shortening

    Take with food
  47. Gabatril
    tiagabine

    anticonvulstant

    AEs: skin reactions

    Take with food
  48. Sabril
    vigabatrin

    Used for refractory seizures

    AEs: vision loss
  49. Fycompa
    perampanel

    anticonvulsant

    AEs: risk of neuropsychiatric events
  50. Azilect
    rasagiline

    selective MAO-B inhibitor used for Parkinson's
  51. Eldepryl, Zelapar ODT
    selegiline

    selective MAO-B inhibitor used for Parkinson's
  52. Emsam patch
    selegiline

    used for depression
  53. Cogentin
    benztropine

    anticholinergic used to treat Parkinson tremors
  54. Comtan
    entacapone

    COMT-inhibitor
  55. Tasmar
    tolcapone

    COMT-inhibitor
  56. Avapro
    irbesartan
  57. Atacand
    candesartan
  58. Benicar
    olmesartan
  59. Micardis
    telmesartan
  60. Edarbi
    azilsartan
  61. Teveten
    eprosartan
  62. Lotensin
    benazepril
  63. Vasotec
    enalapril
  64. Capoten
    captopril
  65. Altace
    ramipril
  66. Univasc
    moexipril
  67. Aceon
    perindopril
  68. Mavik
    trandolapril
  69. Midamore
    amiloride

    potassium-sparing diuretic
  70. Corgard
    nadolol
  71. Sectral
    acebutolol

    ISA*
  72. Zebeta
    bisoprolol
  73. Plendil
    felodipine
  74. Adalat, Procardia
    nifedipine
  75. Sular
    nislodipine
  76. Cardene
    nicardipine
  77. Kapvay
    clonidine

    for ADHD
  78. Intuniv
    guanfacine for ADHD

    central alpha2 agonist
  79. Catapres
    clonidine for resistant HTN

    central alpha2 agonist
  80. Tenex
    guanfacine for resistant HTN

    central alpha2 agonist
  81. Methyldopa
    central alpha2 agonist used in resistant HTN
  82. Zaroxolyn
    metozalone

    thiazide like diuretic
  83. Luminal
    phenobarbital
  84. Primidone
    barbituate -- used in seizures, prodrug of phenobarbital
  85. Librium
    chlordiazepoxide

    Used for alcohol withdrawal and anxiety
  86. Serax
    oxazepam

    • Used for anxiety
    • Less harmful in elderly
  87. Prosam
    estazolam

    Used for sleep
  88. Doral
    quazepam

    Used for sleep
  89. Symbyax
    fluoxetine + olanzapine
  90. Sarafem
    fluoxetine for PMDD
  91. Zonalon
    doxepin for depression

    tertiary TCA
  92. Silenor
    doxepin for sleep

    tertiary TCA
  93. Anafranil
    clomipramine

    tertiary TCA
  94. Tofranil
    imipramine

    tertiary TCA
  95. Vivactil
    protriptyline

    secondary TCA
  96. Pamelor
    nortriptyline

    secondary TCA
  97. Exelon
    rivastigmine

    Ach-esterase inhibitor
  98. Razadyne
    galantamine

    Ach-esterase inhibitor
  99. Geodon
    ziprasidone
  100. Zyprexa
    olanzapine
  101. Latuda
    lurasidone

    atypical antipsychotic
  102. Saphris
    asenapine

    atypical antipsychotic
  103. Nesina
    alogliptin
  104. Tradjenta
    linagliptin
  105. Uloric
    febuxostat

    xanthine oxidase inhibitor
  106. Amerge
    naratriptan
  107. Axert
    almotriptan
  108. Relpax
    eletriptan
  109. Avandia
    rosiglitazone
  110. Humalog
    insulin lispro
  111. Novolog
    insulin aspart
  112. Apidra
    insulin glulisine
  113. Glyset
    miglitol

    alpha-glucosidase inhibitor
  114. Starlix
    neteglinide
  115. Prandin
    repaglinide

    diabetes
  116. Marplan
    isocarboxazid

    MAOI
  117. Nardil
    phenelzine

    MAOI
  118. Parnate
    tranylcypromine

    MAOI
  119. Neupro
    rotigotine

    dopamine agonist
  120. Invega Sustenna
    paliperidone
  121. Relprev
    olanzapine injection
  122. Onsolis
    Fentanyl - buccal
  123. Avinza
    Morphine sulfate ER capsules
  124. Sandimmune, Neoral
    cyclosporine

    Calcineurin inhibitor - Immunosuppressant
  125. Prograf
    tacrolimus

    Calcineurin inhibitor - Immunosuppressant
  126. Sancuso
    granisetron

    Used for chemo-induced N/V

    5HT3 antagonist
  127. VFEND
    voriconazole
  128. Antara, Triglide
    fenofibrate
  129. Altoprev, Mevacor
    lovastatin
  130. Nimotop
    nimodipine
  131. Minitran
    nitroglycerin patch
  132. Monoket
    isosorbide mononitrate

    Dosed less often than dinitrate formulation

    Direct venous vasodilator - reduces preload
  133. Lupron
    leuprolide

    Chemo drug
  134. Mybetriq
    mirabegran

    B3 agonist - relaxes the detrusor muscle

    Used in overactive bladder
  135. Deplin
    l-methylfolate

    Medical food to help treat depression
  136. Diclegis
    pyridoxine (B6) + doxylamine

    for pregnancy induced nausea
  137. Campral
    acamprosate

    Given to alcoholics to decrease desire to drink
  138. Revia
    naltrexone
  139. Betoptic
    betaxolol

    B1 selective eye drop for glaucoma
  140. Cosopt
    timolol + dorzolamide
  141. Combigan
    timolol + brominidine
  142. Istalol, Betimol
    timolol eye drops
  143. Sandostatin
    octreotide
  144. Vimovo
    esomeprazole + naproxen
  145. Feldene
    piroxicam
  146. Tigan
    trimethobenzamide

    antiemetic - given 3 days before receiving apomorphine injections
  147. Exjade
    deferasirox

    Treats iron toxicity -- iron binder
  148. Lotrel
    benazepril + amlodipine
  149. Exforge
    amlodipine + valsartan
  150. Tarka
    verapamil + trandolapril
  151. Azor
    amlodipine + olmesartan
  152. Tekamlo
    aliskiren + amlodipine
  153. Tekturna
    aliskiren
  154. Tribenzor
    amlodipine + olmesartan + HCTZ
  155. Ziac
    bisoprolol + HCTZ
  156. Cardura
    doxazosin
  157. Caduet
    atorvastatin + amlodipine
  158. Vytorin
    simvastatin + ezetimibe
  159. Simcor
    simvastatin + niacin
  160. Vascepa
    Fish oil - EPA only
  161. Juxtapid
    lomitapide

    Inhibits MTP - prevents assembly of lipoproteins

    Preg X; Hepatotoxicity

    Side effects: Diarrhea! N/V
  162. Kynamro
    mipomersen

    Inhibits ApoB synthesis which is main component of LDL

    Preg B; hepatotoxicity
  163. Fragmin
    dalteparin - LMWH
  164. Angiomax
    bivalirudin

    direct thrombin inhibitor; IV only
  165. Iprivask
    desirudin

    direct thrombin inhibitor; SC only
  166. Arixtra
    fondaparinux

    Indirect Factor Xa inhibitor
  167. Kcentra
    4 factor prothrombin complex for warfarin reversal

    Contains factors 2,7,9,10, protein C,S and heparin!

    Administer with vitamin K!!
  168. Ranexa
    ranolazine

    Anti-anginal drug

    QT prolongation
  169. ReoPro
    abciximab

    GP IIb/IIIa antagonist
  170. Integrilin
    eptifibatide

    GP IIb/IIIa antagonist
  171. Aggrastat
    tirofiban

    GP IIb/IIIa antagonist
  172. Effient
    prasugrel

    antiplatelet
  173. Brilinta
    ticagrelor

    antiplatelet
  174. Osmitrol
    mannitol IV

    Used in ICH

    Increase osmotic pressure to reduce intracranial pressure
  175. Nymalize
    nimodipine oral

    CCB for secondary prevention of stroke due to vasospasm after SAH
  176. Larium
    mefloquine 

    • Malaria
    • Dosed once weekly (1-2 weeks before, during,4 weeks after)
    • High degree of resistance!
    • Neuro/pysch AEs

    chloroquine dosed the same, lotsa AE's
  177. Malarone
    Atovaquone/Proguanil

    • Malaria
    • Dosed once daily (1-2 days before, during, 7 days after)
    • NO PREGNANCY

    primaquine dosed the same; test for G6PD for deficiency
  178. Vivotif Berna
    oral typhoid vaccine

    4 capsules - take 1 every OTHER day
  179. Bentyl
    dicyclomine

    antispasmodic used in IBD

    AEs: dizziness, dry mouth, nausea, blurred vision
  180. Lomotil
    diphenoxylate with atropine

    antidiarrheal, Control-CV
  181. Arthrotec
    diclofenac + misoprostol

    combo used for GI protection
  182. Embeda
    morphine + naltrexone
  183. Relistor
    methylnaltrexone

    SC injection for opioid induced constipation
  184. Zutripro
    hydrocodone + chlorpheniramine + pseudoephedrine
  185. Zohydro ER
    hydrocodone ER
  186. Tussagon
    hydrocodone + homatropine
  187. Nucynta
    tapentadol
  188. Vivitrol
    IV naltrexone
  189. Savella
    milnacipran

    SNRI
  190. Serevent
    salmeterol
  191. Symbicort
    formoterol + budesonide
  192. Foradil
    formoterol
  193. QVAR
    beclomethasone
  194. Alvesco
    ciclesonide
  195. Asmanex
    mometasone
  196. Dulera
    mometasone + formoterol
  197. Florinef
    fludrocortisone

    mineralcorticoid - no anti-inflammatory effect!!

    Used in hyponatremia to increase sodium and water retention
  198. Decadron
    dexamethasone
  199. Orapred, Prelone, Milipred
    prednisolone
  200. Xolair
    omalizumab 

    Always give in doctor's office due to high risk of anaphylaxis

    Indicated for moderate to severe persistant asthma (steps 5 or 6)or positive allergic asthma
  201. Colistin, Coly-Mycin
    colistimethate

    Largely nephrotoxic!!

    Used for multi-drug resistant gram negative pathogens

    Polymyxin antibiotic class
  202. Ketek
    telithromycin

    ketolide class - similar to macrolides

    • covers atypicals!
    • FDA approved for CAP only

    QT prolongation, hepatotoxic

  203. Tygacil
    tigecycline

    Related to tetracyclines

    Increased mortality!! Cant reach high enough concentrations in blood since too lipophilic-concentrates in tissues instead

    Good for gram positives (MRSA, VRE), aneroboes, and atypicals, some gram negatives
  204. Xifaxan
    rifaximin

    • Traveler's diarrhea: 200mg TID
    • Hepatic encephalopathy: 550mg BID
  205. Monurol
    fosfomycin

    single dose to treat uncomplicated UTI
  206. Macrobid,Macrodantin
    nitrofurantoin

    Do not use in CrCl <60

    Used for uncomplicated UTI only

    Associated with pulmonary toxicities

    Take with food!
  207. Dificid
    fidaxomicin

    C.diff
  208. Relenza
    zanamivir

    inhaler for flu
  209. Combivent, DuoNeb
    ipratropium + albuterol
  210. Atrovent
    ipratropium
  211. Tudorza
    aclidinium

    LA anticholinergic
  212. Daliresp
    roflumilast

    PDE-4 inhibitor used in severe COPD to reduce inflammation 

    Always use in combo with a long acting anticholinergic!!

    AEs: diarrhea, Nausea, weight loss, depression

    Do not use in moderate-severe HEPATIC impairment
  213. Arcapta
    indacaterol

    LABA
  214. TOBI
    inhaled tobramycin for chronic psudomonas lung infections in cystic fibrosis

    Use 1 month on, then 1 month off
  215. Cayston
    aztreonam inhalation solution for chronic psudomonas lung infections in cystic fibrosis

    1 month on, 1 month off
  216. HyperSal
    hypertonic saline 

    promotes mucus clearance in CF

    Use with a nebulizer
  217. Pulmozyme
    dornase alfa

    promotes mucus clearance in CF

    Once daily via nebulizer, store in fridge
  218. Creon, Pancreaze, Pertyze, Ultresa, Viokace, Zenpep
    pancrelipase - combo of lipase, amylase, and protease

    Used in CF

    Dose adjust based on lipase component and titrate based on stool composition

    TAKE WITH FOOD - not dairy - need low pH (acidic food)

    Viokace - give with PPI
  219. Kalydeco
    ivacaftor

    CFTR potentiator for those with G551D mutation

    Take with high fat food
  220. Kineret
    Anakinra

    IL-1 receptor antagonist for RA

    SC daily
  221. Orencia
    abatacept

    For RA - inhibits T-cell activation

    IV or SQ

    Caution in COPD
  222. Actemra
    tocilizumab

    IL-6 receptor antagonist for RA

    IV

    Increases LFTs
  223. Plaquenil
    hydroxychloroquine

    Anti-malaria drug also used for RA and SLE
  224. Benlysta
    belimumab

    For SLE
  225. CellCept
    mycophenolate mofetil

    Used in transplants and SLE

    AEs: diarrhea

    Empty stomach, no antacids
  226. Copaxone
    glatiramer acetate

    Daily SQ injection for MS
  227. Aubagio
    teriflunomide

    PO medication for MS

    Preg. X and hepatotoxic
  228. Tecfidera
    dimethyl fumarate

    PO med for MS
  229. Gilenya
    fingolimod

    PO med for MS

    AEs: decrease HR -- bradycardia, increased LFTs
  230. Betaseron, Extavia
    Interferon beta-1b

    SQ inj QOD for MS
  231. Avonex (IM), Rebif (SQ)
    Interferon beta-1a

    For MS
  232. Restasis
    cyclosporine eye drops for dry eye

    can take 3-6 months to increase tear production
  233. Salagen
    pilocarpine for dry mouth
  234. Leucovorin
    folic acid analog
  235. Rituxan
    rituximab

    IV drug for RA or cancer

    Depletes CD20 B cells

    BBW: fatal infusion reactions, PML, tumor lysis syndrome, fatal skin reactions
  236. Cyclophosphamide
    IV drug for SLE and cancer

    Cytotoxic

    Hemorrhagic cystitis - give mesna, hydration

    May also cause infertility, infections, and bone marrow suppression
  237. Myfortic
    mycophenolic acid 

    Used in transplants

    Used in combos with CNIs - 1st line

    AEs: diarrhea

    Empty stomach, no antacids
  238. Simulect
    basiliximab

    First line induction agent in transplants
  239. Nulojix
    belatacept

    IV infusion - maintenance for transplants

    AEs: Increased risk of PTLD, must have immunity to EBV
  240. Zortress, Afinitor
    everolimus

    Oral transplant drug
  241. Rapamune
    siroliums

    Transplant drug
  242. Multaq
    dronedarone
  243. Tikosyn
    dofetilide
  244. Protopic
    topical tacrolimus

    used for eczema; 2nd line
  245. Elidel
    topical pimecrolimus

    used for eczema; 2nd line
  246. Temovate
    clobetasol

    Very high potency
  247. Diprolene
    betamethasone

    Very high/high potency steroid
  248. Vanos, Lidex
    fluocinonide

    Very high/high potency steroid
  249. Elocon
    mometasone

    high/medium potency
  250. Westcort
    hydorcortisone valerate

    low/medium potency
  251. Kenalog
    triamcinolone

    medium potency
  252. Derma-Smoothe
    fluocinolone

    low potency
  253. Precedex
    dexmedetomidine

    DOC for ICU delirium sedation
  254. Flolan, Veletril
    epoprostenol

    prostacyclin analogue

    Potent vasodilator used in PAH
  255. Remodulin, Tyvaso
    treprostinil

    prostacyclin analogue used in PAH

    • Remodulin - very painful SQ injection
    • Tyvaso - inhaled
  256. Ventavis
    iloprost

    prostacyclin analogue used in PAH

    Inhaled
  257. Tracleer
    bosentan

    endothelin receptor antagonist used in PAH

    REMS drug - hepatotoxic, preg. X

    Can cause anemia
  258. Letairis
    ambrisentan

    endothelin receptor antagonist used in PAH

    REMS - preg X
  259. Opsumit
    macitentan

    endothelin receptor antagonist for PAH

    REMS - preg. X
  260. Revatio
    sildenafil for PAH
  261. Adcirca
    tadalafil for PAH
  262. Adempas
    riociguat

    soluble guanylate cyclase stimulator for both PAH and CTEPH

    REMS - preg. X

    Do not give with nitrates!! Smoking increases clearance
  263. Emend
    aprepitant or fosprepitant (IV)

    Substance P/Neurokinin-1 receptor antagonists

    Used for acute and delayed nausea before chemo
  264. Zometa
    zolendronic acid given IV monthly

    Used in hypercalcemia of malignancy to prevent skeletal-related events

    (Reclast is the osteoporosis drug)

    Give in combo with calcitonin!
  265. Xgeva
    denosumab given SQ monthly

    Used for bone metasteses

    (Prolia is the osteoporosis drug given every 6 months)
  266. Camptosar
    irinotecan

    AE: DIARRHEA

    "I run to the can"

    Pre-treat with atropine or delayed with loperamide
  267. VePesid
    etoposide

    Topo-II inhibitor for cancer chemo

    AE: hypotension if given too fast
  268. Casodex
    bicalutamide

    antiandrogen for prostate cancer
  269. Femara
    letrozole

    aromatase inhibitor for prevention of breast cancer recurrence

    POST-menopause only; must be ER/PR+

    AEs: osteoporosis
  270. Soltamox
    tamoxifen for prevention of breast cancer recurrence

    SERM drug, given pre or post menopause, must be ER/PR+

    increases risk of endometrial cancer
  271. Arimidex
    anastrozole
  272. Aromasin
    exemastane
  273. Selzentry
    maraviroc

    CCR5 inhibitor - entry inhibitor

    hepatotoxic
  274. Fuzeon
    enfuvirtide

    fusion inhibitor

    local injection site reaction
  275. Sustiva
    efavirenz

    NNRTI
  276. Atripla
    efavirenz + emtricitabine + tenofovir
  277. Complera
    rilpivirine + emtricitabine + tenofovir
  278. Intelence
    etravirine

    can use this even if resistance to other NNRTIs
  279. Ziagen
    abacavir

    NRTI
  280. Epzicom
    abacavir + lamivudine
  281. Videx
    didanosine

    NRTI
  282. Emtriva
    emtricitabine

    NRTI
  283. Truvada
    emtricitabine + tenofovir
  284. Epivir
    lamivudine

    NRTI
  285. Retrovir
    zidovudine

    NRTI
  286. Reyataz
    atazanavir

    protease inhibitor
  287. Kaletra
    lopinavir + ritonavir
  288. Isentress
    raltegravir

    integrase inhibitor
  289. Viread
    tenofovir
  290. Hepsera
    adefovir

    NRTI for Hep B
  291. Baraclude
    entecavir

    NRTI for Hep B
  292. Copegus
    ribavirin

    For Hep C in combo wth interferon alfa

    Preg X
  293. Victrelis
    boceprevir
  294. Imdur
    isosorbide mononitrate
  295. Minitran
    nitrogylcerin
  296. PhosLo
    calcium acetate

    1st line for hyperphosphatemia

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