Pharm

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Author:
yagurl_dana
ID:
27834
Filename:
Pharm
Updated:
2010-07-24 14:10:14
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Cholinergic Blocking drugs
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Description:
Unit 30
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  1. What are Cholinergic BLOCKING drugs?
    They block the action of the neurotransmitter acetylcholine in the parasympathetic nerve SYNAPSE.

    Some of the drugs inhibit nerve impulses @ both muscarinic & nicotinic receptors that effect organ & structures of the body like eyes, respiratory, GI tracts, heart, bladder
  2. What are Cholinergic BLOCKING drugs used for?
    • Pylorospasm adn peptic ulcer
    • Ureteral or biliary colic & bladder overactivity
    • vegal nerve - induced by bradycardia
    • Parkinsonism
    • Preop reduction of oral secretions
  3. What are the A/R for Cholinergic BLOCKING drugs?
    NURSE = THE SEVERITY OF MANY OF A/R IS OFTEN DOSE-DEPENDENT THAT IS, THE LARGER THE DOSE, THE MORE INTENSE ADVERSE REACTION.

    • GI REACTION:
    • Dry mouth, nausea, vomiting
    • Difficulty in swallowing, heartburn
    • Constipation

    • CNS REACTIONS:
    • Headache, flushing, nervousness
    • Drowsiness, weakness, insomnia
    • Nasal congestion, fever

    • Visual Reaction:
    • Blurred vision
    • Mydriasis (dilation of pupil)
    • Photophobia
    • Cycloplegia (inability 2 focus the eye)
    • Increased ocular tension

    • GENITOURINARY REACTIONS:
    • Urinary hesitancy & retention
    • Dysuria

    • Cardiovascular reactions:
    • Palpitation
    • Bradycardia (after low doses of Atropine)
    • Tachycardia (after high doses of Atropine)

    • Other:
    • Urticaria
    • Decreased sweat production
    • Anaphylatic shock
    • Rash
  4. What is drug idiosyncrasy?
    an unexpected or unusual drug effect.

    Example: SCOPOLAMINE may occasionally cause excitement, delirium, and restlessness.
  5. What are other names 4 Cholinergic BLOCKING drugs?
    • Anticholinergic drugs
    • Cholinergic blockers
    • Parasympatholytic drugs
  6. What patients are contraindicated in using Cholinergic BLOCKING drugs?
    • With hypersensitivity 2 drugs or GLAUCOMA
    • Myasthenia Gravis
    • Tachyarrhythmias
    • Myocardial infarction
    • Congestive heart failure (unless bradycardia is present)
  7. Use Cholinergic BLOCKING drugs with caution with patients with?
    • GI infections
    • Benign prostatic hypertrophy
    • urinary retention
    • hyperthyroidism
    • hepatic or renal disease
    • hypertension

    USE ATROPINE W/ CAUTION IN PEEPS W/ ASTHMA
  8. What is the Nurse's preadministrative assessment b4 giving Cholinergic BLOCKING drugs?
    • Get health hx and s/s hx
    • Get b/p, pulse, & respiratory rate
    • Check stool of pt's who hv peptic ulcer 4 color look 4 occult blood
    • Check 4 visual acuity 4 peeps w/ glaucoma
    • look 4 signs of dehydration
    • weighing the client if prolonged diarrhea

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