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What are Cholinergic BLOCKING drugs?
They block the action of the neurotransmitter acetylcholine in the parasympathetic nerve SYNAPSE.
Some of the drugs inhibit nerve impulses @ both muscarinic & nicotinic receptors that effect organ & structures of the body like eyes, respiratory, GI tracts, heart, bladder
What are Cholinergic BLOCKING drugs used for?
- Pylorospasm adn peptic ulcer
- Ureteral or biliary colic & bladder overactivityvegal nerve - induced by bradycardia
- Preop reduction of oral secretions
What are the A/R for Cholinergic BLOCKING drugs?
NURSE = THE SEVERITY OF MANY OF A/R IS OFTEN DOSE-DEPENDENT THAT IS, THE LARGER THE DOSE, THE MORE INTENSE ADVERSE REACTION.
Dry mouth, nausea, vomiting
- Difficulty in swallowing, heartburn
- CNS REACTIONS:
- Headache, flushing, nervousness
- Drowsiness, weakness, insomnia
- Nasal congestion, fever
- Visual Reaction:
- Blurred vision
- Mydriasis (dilation of pupil)
- Cycloplegia (inability 2 focus the eye)
- Increased ocular tension
- GENITOURINARY REACTIONS:
- Urinary hesitancy & retention
- Cardiovascular reactions:
- Bradycardia (after low doses of Atropine) Tachycardia (after high doses of Atropine)
- Decreased sweat production
- Anaphylatic shock
What is drug idiosyncrasy?
an unexpected or unusual drug effect.
Example: SCOPOLAMINE may occasionally cause excitement, delirium, and restlessness.
What are other names 4 Cholinergic BLOCKING drugs?
- Anticholinergic drugs
- Cholinergic blockers
- Parasympatholytic drugs
What patients are contraindicated in using Cholinergic BLOCKING drugs?
- With hypersensitivity 2 drugs or GLAUCOMA
- Myasthenia Gravis
- Myocardial infarction
- Congestive heart failure (unless bradycardia is present)
Use Cholinergic BLOCKING drugs with caution with patients with?
USE ATROPINE W/ CAUTION IN PEEPS W/ ASTHMA
- GI infections
- Benign prostatic hypertrophy
- urinary retention
- hepatic or renal disease
What is the Nurse's preadministrative assessment b4 giving Cholinergic BLOCKING drugs?
- Get health hx and s/s hx
- Get b/p, pulse, & respiratory rate
- Check stool of pt's who hv peptic ulcer 4 color look 4 occult blood
- Check 4 visual acuity 4 peeps w/ glaucomalook 4 signs of dehydration
- weighing the client if prolonged diarrhea