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What autocoid agonists are there?
What are prostaglandins derived from?
What do systemic prostaglandins do?
- Concentrate in areas of inflammation
- Promote pain and fever
- Inhibit gastric secretions
What are prostaglandin synthesis inhibitors?
What is serotonin used for
- Treating migraine headaches
- Prozac and Zoloft
What drugs are 1st generation h1 blockers?
- Chlorpheniramine maleate
What drugs are 2nd generation h1 blockers
What drugs are H2 blockers
What drugs are used for bronchodilation?
- Advair diskus
What bronchodilating drugs are fast acting?
What is the MOA of H2 blockers?
Block acid secretion from parietal cells
What H2 blocker can cause gynecomastia and loss of libido?
What proton pump inhibitors are there?
What is the MOA of methotrexate?
Interferes with formation of essential cellular components
What is methotrexate used for?
What is tamoxifen used for
Tx of breast cancer
What are adverse effects of tamoxifen?
- Crystalline retinopathy
- Hot flashes
- Increases the risk of uterine cancer
What does iodine kill?
what antiviral is used against influenza A, B, and Avian flu?
How do antiherpetic drugs work?
Inhibit viral DNA synthesis by selectively acting on DNA polymerase
What drugs are used to treat HSV?
- acyclovir PO 400mg
- valacyclovir PO
What is the DOC for HSV keratitis?
What drug is available for Hep C?
What is the MOA of ribavirin?
Inhibits RNA polymerase
What antivirals treat CMV?
When is CMV found?
It is opportunistic in AIDS retinopathy
What CMV drug can be delivered as an intraocular sustained release implant?
what drug is given to treat CMV when ganciclovir fails?
What is the 3rd line tx for CMV
What are major side effects of cidofovir?
What drug is used to treat HIV?
What drugs are included in the HIV cocktail?
What antifungal is the only one for fungal keratitis?
Which antifungal is the only one NOT to involve ergosterol
What is the MOA of natamycin?
Binds to ergsterol and forms pores in cell wall
What antifungal drug has the narrowest spectrum?
What antifungal drugs are there?
- Amphotericin B