Define: Alpha-1 Beta Blocker
a variety of drugs that block α1-adrenergic receptors in arteries, smooth muscles and central nervous system tissues.
The blockade or reduction of epinephrine and norepinephrine binding on alpha adrenoreceptors reduce arteriolar resistance and increase venous capacitance causes reflex tachycardia. Depending on plasma concentration they may cause postural hypotension. Alpha-1 blockers may decrease LDL and triglycerides and increase HDL.