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The flashcards below were created by user
kimiko
on FreezingBlue Flashcards.
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Streptococcus pyogenes
"flesh eating bacteria" that produces an endotoxin known as a super antigen that activates T cells and causes the overproduction of cytokines
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Staphylococcus
- INVASIVE gram positive cocci that resemble a bunch of grapes
- they cause pus forming diseases in humans
- normally found in respiratory system and skin
- can cause disease in many organs
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S. Aureus
- Toxic Shock Syndrome
- bacterial TSST - 1 protein binds to MHC class 2 and TCR
- TOXIN stimulates T cell responses in the absence of a specific peptide
- Cytokine overproduction (shock due to circulatory collaps and organ failure
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Methicillin - Resistant S. aureus (MRSA)
- many strains are drug-resistant
- MRSA strains typically acquired as nosocomial infections
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what is critical for reducing MRSA in health care settings?
good aseptic techniques
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what causes antibiotic associated colitis?
when antibiotic use kills normal flora and Clostridium Difficile take over in the gut. this leads to toxin production and sporulation
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what are the signs and symptoms of clostridium difficult?
colitis, toxic megacolon, can lead to sepsis and death
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what is a novel approach to treating C. Diff?
transplant of normal bacteria from another person delivered into the colon ("bacteriotherapy" or "fecal transplantation")
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What bacteria causes tuberculosis?
mycobacterium tuberculosis
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what are commonly infected groups of TB (tuberculosis)?
homeless, alcoholics, prisoners, immigrants
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at what pace does TB progress?
slowly
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how is TB transmitted?
reactivation of old dormant infections
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what are virulence factors of Mtb?
- unique toxic cell envelope components
- Survive phagocytosis
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what is the course of disease for TB?
lung
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