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what is the cause of most cases of osteomyelitis?
in patients with UTI or IVDU, which are most common organisms to cause osteomyelitis?
- Pseudomonas aeruginosa
in neonates,which are most common organisms to cause osteomyelitis?
haemophilus influenza, group B strep
in sickle cell, which are most common organisms to cause osteomyelitis?
what is rheumatoid factor?
IgM autoAb against the Fc portion of IgG
what is the key event in the pathogenesis of RA?
- pannus: inflamed, cellular synovial tissue which has proliferative properties, causes cartilage erosion
- can infiltrate capsule, ligaments and other supportive structures leading to subluxation and deformities as well as erosion of the bone
which type of systemic sclerosis do you get oesophageal involvement in? and which Ab?
- limited (remember CREST)
What are the bone metastases in prostatic cancer like?
what is impetigo? and treatment?
- pyogenic infection of EPIDERMIS
- usually S.aureus
- Rx: flucloxacillin
what is furunculosis?
- infection of sebaceous gland caused by S.aureus
- surgically drain abscess and give fluclox
what is scalded skin syndrome?
caused by exfoliating made by S.aureus
what is erysipelas? and cause? spread? and Rx?
- intradermal infection caused by strep progenies
- indurated hot tender red lesion clearly DEMARCATED from normal skin
- spreads rapidly via lYMPHATICS, n.b. blood cultures usually negative
- regional lymphadenopathy
- treated with iv benpen
what is cellulitis?
- infection of subcutaneous tissue
- s.pyogenes or s.aureus
what is gas gangrene? cause? Rx?
- clostridium perferingens infection of subcut and muscle tissue
- usually from war/field sports wounds
- Rx: benpen / metronidazole and surgical debridement
what is necrotising fasciitis?
- rapidly spreading infection that causes necrotic liquefaction of subcut FAT
- usually polymicrobial, skin and gut flora.
- Rx: debride and broad spec abx
out of CT and MRI, which is better for bone?
out of CT and MRI, which is better for soft tissue?
which part of the skeleton is most commonly affected by bony mets and which is rarely affected?
- most common: skull
- rare: tibia
what happens if you get ulnar nerve lesion at the wrist and why?
clawing of the hand due to action of unopposed long flexors
which nerve is damaged in foot drop and which action is lost? where is the sensory loss?
- common peroneal nerve
- cannot dorsiflex the foot
- sensory loss to dorsum of foot
which spinal nerve roots is in sciatic nerve? what does it suppler? what are branches of sciatic nerve?
- supplies: hamstrings
- branches to give tibial and common peroneal nerve
in De Quervain's tenosynovitis, which tendons are concerned?
- extensor pollicis brevis
- abductor pollicis longus
in finklesteins test, where is the pain reproduced?