Biochemical Foundations of Physiology -3 Part

Where does the TCA Cycle occur ?

Is it a aerobic or anaerobic process ?

Before the cycle begins pyruvate is converted to acetyl CoA by what complex ?

What makes up the pyruvate dehydrogenase
complex ? Each catalyze part of the overall reaction

How many coenzymes does PDH have ?

What are the coenzymes for PDH ?

1.Pyruvate dehydrogenase (E1)
2.Dihydrolipoyl transacetylase (E2)
3.Dihydrolipoyl dehydrogenase (E3)

Arsenic poisoning is due primarily to inhibition of enzymes that require what coenzyme ?

A deficiency of Pyruvate dehydrogenase (E1) will cause what ?

The inability to convert pyruvate to acetyl CoA will make ?

What are the NADH producing step in the TCA cycle ?

What are the FADH producing steps in the TCA cycle ?

What are the GTP producing step in the TCA cycle ?

The condensation of acetyl CoA and oxaloacetate to form citrate is catalyzed by what enzyme ?

Citrate is isomerized to isocitrate by what enzyme ?

What enzyme  catalyzes the irreversible oxidative decarboxylation of isocitrate to form α-ketoglutarate ?

The conversion of α-ketoglutarate to succinyl CoA is catalyzed by what enzyme ?

The cleavage of succinyl CoA to form succinate is catalyzed by the what
enzyme ?

Succinate is oxidized to fumarate by what enzyme ?

What  is the only enzyme of the TCA cycle
that is embedded in the inner mitochondrial membrane ?

Fumarate is hydrated to malate by what enzyme ?

Malate is oxidized to oxaloacetate by what enzyme ?

The most important of TCA's 
these regulated enzymes are those that catalyze reactions with highly negative ∆Go: Which are they ?

What is the gross and net production of ATP for glycolysis ?

Where is gluconeogensis taking place overnight ?

What about a prolonged fast ?