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tags "Pharmacologygroup1 LVAPEC"
folders "Cardiology Pharmacology"
Slows conduction time through the AV node
Can interupt re-entrant pathways
Acts directly on Sinus Pacemaker cells
Drug of choice for re-entry SVT
Can be used diagnostically for stable, wide complex Tachycardia(suspected SVT with aberrancy)
Regular Tachycardia(narrow and wide)
Conversion of PSVT to sinus rhythm
May convert re-entry SVT due to Wolf-Parkinson-White syndrome
Not effective in converting A-Fib/Flutter or V-Tach
Torsades de Pointes(Polymorphic V-Tach)
2nd or 3rd heart block
Sick sinus syndrome
Poison induced Tachycardia
Adult: 6mg over 1-3sec, followed by 20mL saline flush and elevate extremity. If no response after 1-2mins administer 12mg over 1-3sec. Max total dose 30mg
Peds: 0.1-0.2mg/kg rapid IV. Max single dose 12mg
Adenosine (Adenocard) Drug interactions
Methylxanthines antagonize the effects
Diprydamole potentiates the effects
Carbamazepine potentiate the AV node blocking the effects
Bronchoconstrictions in asthmatics
Adenosine (Adenocard) special consideration
Short half life limits side effects in most pts.
Arrhythmia including blocks are common at the time of conversion.
Should be administered into a large bore IV closest to pts heart and flushed.
Drug Profiles,Cardiology Pharmacology