Adenosine(Adenocard)

Card Set Information

Author:
Lhernandez
ID:
283029
Filename:
Adenosine(Adenocard)
Updated:
2015-01-27 01:35:20
Tags:
LVAPEC
Folders:
Drug Profiles,Cardiology Pharmacology
Description:
Adenosine
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  1. author "Lhernandez"
    • tags "Pharmacologygroup1 LVAPEC"
    • folders "Cardiology Pharmacology"
    • description "
  2. Adenosine(Adenocard) Mech
    • Slows conduction time through the AV node
    • Can interupt re-entrant pathways
    • Slows HR
    • Acts directly on Sinus Pacemaker cells
    • Drug of choice for re-entry SVT
    • Can be used diagnostically for stable, wide complex Tachycardia(suspected SVT with aberrancy)
  3. Adenosine(Adenocard) Indication
    • Regular Tachycardia(narrow and wide)
    • Conversion of PSVT to sinus rhythm
    • May convert re-entry SVT due to Wolf-Parkinson-White syndrome
    • Not effective in converting A-Fib/Flutter or V-Tach
  4. Adenosine(Adenocard) Contra
    • Torsades de Pointes(Polymorphic V-Tach)
    • 2nd or 3rd heart block
    • Sick sinus syndrome
    • A-Fib/Flutter
    • V-Tach
    • Hypersensitivity
    • Poison induced Tachycardia
  5. Adenosine(Adenocard) Adverse
    • Facial flushing
    • SOB
    • C/P
    • Headache
    • Paresthesia
    • Diaphoresis
    • Palpitations
    • Hypotension
    • Nausea
  6. Adenosine(Adenocard) Dosage
    Adult: 6mg over 1-3sec, followed by 20mL saline flush and elevate extremity. If no response after 1-2mins administer 12mg over 1-3sec. Max total dose 30mg

    Peds: 0.1-0.2mg/kg rapid IV. Max single dose 12mg
  7. Adenosine (Adenocard) Drug interactions
    • Methylxanthines antagonize the effects
    • Diprydamole potentiates the effects
    • Carbamazepine potentiate the AV node blocking the effects
    • Bronchoconstrictions in asthmatics
  8. Adenosine (Adenocard) special consideration
    • Short half life limits side effects in most pts.
    • Arrhythmia including blocks are common at the time of conversion.
    • Should be administered into a large bore IV closest to pts heart and flushed.

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